Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 6/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | KCNE1 | P15382 | 2/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.42 |
| ▸ | SCN1A | P35498 | 2/20 | 0.42 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.42 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12488384 | 0.84 | KCNA5 (0.51) | KCNA5KCNH2CYP1A2ALDH1A1TSHR | |
| SCHEMBL506747 | 0.79 | KCNA5 (0.50) | KCNA5KCNH2CYP1A2ALDH1A1TSHR | |
| SCHEMBL7306903 | 0.79 | SLC6A3 (0.45) | KCNA5KCNH2CYP1A2ALDH1A1TSHR | |
| SCHEMBL29520435 | 0.78 | TSHR (0.62) | KCNA5KCNH2CYP1A2ALDH1A1TSHR | |
| SCHEMBL65284 | 0.78 | TSHR (0.62) | KCNA5KCNH2CYP1A2ALDH1A1TSHR | |
| SCHEMBL3910230 | 0.78 | TSHR (0.62) | KCNA5KCNH2CYP1A2ALDH1A1TSHR | |
| SCHEMBL6000902 | 0.78 | KCNA5 (0.46) | KCNA5KCNH2CYP1A2ALDH1A1TSHR | |
| SCHEMBL6196919 | 0.77 | ALDH1A1 (0.51) | KCNA5KCNH2CYP1A2ALDH1A1TSHR | |
| SCHEMBL9185638 | 0.77 | SLC6A3 (0.56) | KCNA5KCNH2CYP1A2ALDH1A1TSHR | |
| SCHEMBL506917 | 0.77 | KCNA5 (0.52) | KCNA5KCNH2CYP1A2ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109338425-B | Zinc-nickel and nickel-tungsten electroplating solution and preparation method and electroplating method thereof | 胜利油田胜机石油装备有限公司 | 2020-01-10 | — | — | CN | claimed |
| WO-2023141852-A1 | CDK2 INHIBITORS, PREPARATION METHOD THEREFOR AND USE THEREOF | 益方生物科技(上海)股份有限公司 | 2023-08-03 | — | — | WO | disclosed |
| CN-116323558-A | Compounds and methods for treating diseases | 艾特里提治疗有限公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-115928162-A | Alloy electroplating solution for overhead transmission line tower and electroplating method thereof | 国网辽宁省电力有限公司锦州供电公司 | 2023-04-07 | — | — | CN | disclosed |
| CN-115928162-A | Alloy electroplating solution for overhead transmission line tower and electroplating method thereof | 国网辽宁省电力有限公司锦州供电公司 | 2023-04-07 | — | — | CN | disclosed |
| CN-114787150-A | Alkynyl quinazoline compounds | 黑钻治疗公司 | 2022-07-22 | — | — | CN | disclosed |
| CN-109338425-B | Zinc-nickel and nickel-tungsten electroplating solution and preparation method and electroplating method thereof | 胜利油田胜机石油装备有限公司 | 2020-01-10 | — | — | CN | disclosed |
| US-8653269-B2 | Process for preparation of t-butoxycarbonylamine compounds | NIPPON SODA CO., LTD. (JP) | 2014-02-18 | — | — | US | disclosed |
| EP-2546235-A1 | PROCESS FOR PREPARATION OF t-BUTOXYCARBONYLAMINE COMPOUNDS | Nippon Soda Co., Ltd. (JP) | 2013-01-16 | — | — | EP | disclosed |
| US-20130005981-A1 | PROCESS FOR PREPARATION OF t-BUTOXYCARBONYLAMINE COMPOUNDS | NIPPON SODA CO., LTD. (JP) | 2013-01-03 | — | — | US | disclosed |
| US-20070032466-A1 | Drug containing chymase inhibitor as the active ingredient | TEIJIN PHARMA LIMITED (JP) | 2007-02-08 | — | — | US | disclosed |
| EP-1666067-A1 | DRUG CONTAINING CHYMASE INHIBITOR AS THE ACTIVE INGREDIENT | Teijin Pharma Limited (JP) | 2006-06-07 | — | — | EP | disclosed |
| WO-2002087587-A2 | 4-AMINOSULFONYLQUINAZOLINES AND -QUINOLINES AS TYROSINE KINASE INHIBITORS | CELLTECH R & D LIMITED (GB) | 2002-11-07 | — | — | WO | disclosed |
| US-6300337-B1 | Acetamide derivative and use thereof | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2001-10-09 | — | — | US | disclosed |
| US-6271238-B1 | USEFUL IN TREATING AND PREVENTING DISEASES INVOLVING CHYMOTRYPSIN TYPE PROTEASES WHICH ARE RELATED TO ASTHMA, ALLERGY, INFLAMMATIONS, RHEUMATISM, HYPERTENSION, HEART FAILURE, MYOCARDIAL INFARCTION, AND CARDIAC HYPERTROPHY | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2001-08-07 | — | — | US | disclosed |
| EP-1055683-A1 | NOVEL ACETAMIDE DERIVATIVE AND USE THEREOF | Nippon Kayaku Kabushiki Kaisha (JP) | 2000-11-29 | — | — | EP | disclosed |
| EP-0936216-A1 | NOVEL ACETAMIDE DERIVATIVES AND PROTEASE INHIBITORS | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1999-08-18 | — | — | EP | disclosed |
| US-5912256-A | 0-(4-INDOLYLOXY)-3-(4-HYDROXY-4-NAPHTHYLPIPERIDIN-1-YL)PROPANE S | ELI LILLY AND COMPANY (US) | 1999-06-15 | — | — | US | disclosed |
| EP-0814084-A1 | Indole derivatives as 5-HT1A antagonists and as inhibitors of serotonine reuptake | ELI LILLY AND COMPANY (US) | 1997-12-29 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130005981-A1 | PROCESS FOR PREPARATION OF t-BUTOXYCARBONYLAMINE COMPOUNDS | BPGM, TST, BET1 | KCNA5 2820/4885KCNH2 1116/4885CYP1A2 3292/4885 |
| US-20070032466-A1 | Drug containing chymase inhibitor as the active ingredient | REN, SERPINB1, CMA1 | KCNA5 3335/4885KCNH2 3354/4885CYP1A2 4217/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.