Tetroquinone

Tetroquinone

SCHEMBL565084

O.O=C1C(O)=C(O)C(=O)C(O)=C1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO

The experimentally established mechanism targets of Tetroquinone. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MEN1 known ✓ O00255 2/20 0.90
KDM4E B2RXH2 3/20 1.00
ALDH1A1 P00352 3/20 1.00
TDP1 Q9NUW8 2/20 1.00
LMNA P02545 1/20 1.00
HSD17B10 Q99714 1/20 1.00
MAPT P10636 2/20 0.90
KMT2A Q03164 2/20 0.90
ALOX15 P16050 1/20 0.90
ALOX12 P18054 1/20 0.90
BLM P54132 1/20 0.90
APAF1 O14727 1/20 0.44
TDP2 O95551 1/20 0.44
DUSP3 P51452 1/20 0.35
HPGD P15428 1/20 0.32
RECQL P46063 1/20 0.32
SENP1 Q9P0U3 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tetroquinone SCHEMBL10609095 1.00 KDM4E (1.00) KDM4EALDH1A1TDP1LMNAHSD17B10
Tetroquinone SCHEMBL167587 0.95 KDM4E (1.00) KDM4EALDH1A1TDP1LMNAHSD17B10
Tetroquinone SCHEMBL30687945 0.90 KDM4E (0.90) KDM4EALDH1A1TDP1LMNAHSD17B10
Tetroquinone SCHEMBL28458147 0.90 KDM4E (0.90) KDM4EALDH1A1TDP1LMNAHSD17B10
Tetroquinone SCHEMBL29249657 0.90 KDM4E (0.90) KDM4EALDH1A1TDP1LMNAHSD17B10
Tetroquinone SCHEMBL30687946 0.90 KDM4E (0.90) KDM4EALDH1A1TDP1LMNAHSD17B10
Tetroquinone SCHEMBL31259898 0.90 KDM4E (0.90) KDM4EALDH1A1TDP1LMNAHSD17B10
Tetroquinone SCHEMBL10666573 0.90 KDM4E (0.90) KDM4EALDH1A1TDP1LMNAHSD17B10
Tetroquinone SCHEMBL28209010 0.90 KDM4E (0.90) KDM4EALDH1A1TDP1LMNAHSD17B10
SCHEMBL13801532 0.90 KDM4E (0.90) KDM4EALDH1A1TDP1LMNAHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 174 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119977819-A Organic electric energy transfer eutectic crystal with near infrared light thermal characteristics and preparation method of light heat storage fiber thereof 苏州大学 2025-05-13 CN claimed
CN-118419976-A Lamellar vanadium-based material capable of regulating interlayer spacing by utilizing solvent molecules/electrochemical active organic molecules, and preparation method and application thereof 石河子大学 2024-08-02 CN claimed
CN-117434125-A Electrochemical biosensor based on copper-based conductive metal organic framework modification and preparation method and application thereof 中国科学院大连化学物理研究所 2024-01-23 CN claimed
EP-4304638-A1 USES OF AMPHIPHILES IN IMMUNE CELL THERAPY AND COMPOSITIONS THEREFOR Elicio Therapeutics, Inc. (US) 2024-01-17 EP claimed
US-11859047-B2 Polycarbonate resin composition and article including the same LG CHEM, LTD. (KR) 2024-01-02 US claimed
US-20230380457-A1 Materials and Methods for Extending Shelf-Life of Foods JP LABORATORIES, INC. 2023-11-30 US claimed
EP-4280882-A2 MATERIALS AND METHODS FOR EXTENDING SHELF-LIFE OF FOODS JP LABORATORIES, INC. (US) 2023-11-29 EP claimed
US-20230363426-A1 Materials and Methods for Extending Shelf-Life of Foods JP LABORATORIES, INC. 2023-11-16 US claimed
US-11793220-B2 Materials and methods for extending shelf-life of foods JP LABORATORIES, INC. (US) 2023-10-24 US claimed
CN-116916755-A Materials and methods for extending the shelf life of food products JP实验室公司 2023-10-20 CN claimed
EP-3097169-A1 CONSUMER PRODUCT COMPOSITIONS The Procter & Gamble Company (US) 2016-11-30 EP claimed
US-20150210963-A1 Systems and Methods for Treating a Surface THE PROCTER & GAMBLE COMPANY 2015-07-30 US claimed
US-20150210964-A1 Consumer Product Compositions THE PROCTER & GAMBLE COMPANY 2015-07-30 US claimed
WO-2015112667-A1 SYSTEMS AND METHODS FOR TREATING A SURFACE THE PROCTER & GAMBLE COMPANY (US) 2015-07-30 WO claimed
WO-2015112671-A1 CONSUMER PRODUCT COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2015-07-30 WO claimed
US-7384533-B2 Electrolytic processes with reduced cell voltage and gas formation 3M INNOVATIVE PROPERTIES COMPANY (US) 2008-06-10 US claimed
WO-2003035941-A2 ELECTROLYTIC PROCESSES WITH REDUCED CELL VOLTAGE AND GAS FORMATION 3M INNOVATIVE PROPERTIES COMPANY (US) 2003-05-01 WO claimed
EP-0801089-A1 Preparation of branched polycarbonates THE COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 1997-10-15 EP claimed
US-5663029-A DEVELOPMENT OF LATENT IMAGE, TRANSFERRING TO FORM RECORDING SHEETS, COATING A SUBSTRATE USING POLYMERS XEROX CORPORATION (US) 1997-09-02 US claimed
EP-0667245-A1 Recording sheets containing alcohols and saccharides XEROX CORPORATION (US) 1995-08-16 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150210963-A1 Systems and Methods for Treating a Surface HMBS, PPOX, TTPA MEN1 4665/4885KDM4E 4428/4885ALDH1A1 1283/4885
US-20150210964-A1 Consumer Product Compositions NQO1, TYR, ETFA MEN1 3836/4885KDM4E 3331/4885ALDH1A1 27/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.