Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | CTSL | P07711 | 5/20 | 0.50 |
| ▸ | CTSB | P07858 | 4/20 | 0.50 |
| ▸ | CTSS | P25774 | 2/20 | 0.50 |
| ▸ | CTSK | P43235 | 2/20 | 0.50 |
| ▸ | TACR1 | P25103 | 3/20 | 0.48 |
| ▸ | MMP8 | P22894 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5651942 | 1.00 | ALDH1A1 (0.55) | ALDH1A1ALOX15CTSLCTSBCTSS | |
| SCHEMBL996293 | 0.85 | L3MBTL1 (0.58) | ALDH1A1ALOX15CTSLCTSBCTSS | |
| SCHEMBL3769914 | 0.85 | L3MBTL1 (0.58) | ALDH1A1ALOX15CTSLCTSBCTSS | |
| SCHEMBL996291 | 0.85 | L3MBTL1 (0.58) | ALDH1A1ALOX15CTSLCTSBCTSS | |
| SCHEMBL10964365 | 0.85 | MMP8 (0.56) | ALDH1A1ALOX15CTSLCTSBCTSS | |
| SCHEMBL8244008 | 0.84 | ALDH1A1 (0.59) | ALDH1A1ALOX15CTSLCTSBCTSS | |
| Hydrochloric Acid SCHEMBL28046933 | 0.84 | L3MBTL1 (0.57) | ALDH1A1ALOX15CTSLCTSBCTSS | |
| SCHEMBL7460396 | 0.84 | POLB (0.64) | ALDH1A1ALOX15POLBGAARAB9A | |
| Hydrochloric Acid SCHEMBL27371193 | 0.84 | L3MBTL1 (0.57) | ALDH1A1ALOX15CTSLCTSBCTSS | |
| SCHEMBL6154220 | 0.84 | L3MBTL1 (0.48) | ALDH1A1ALOX15CTSSCTSKRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7307184-B2 | Processes for preparing oxazolidinone derivatives of β-hydroxyethlamine compounds and for preparing β-hydroxyethlamine compounds | KANEKA CORPORATION (JP) | 2007-12-11 | — | — | US | disclosed |
| US-20060135784-A1 | PROCESS FOR PRODUCING 3-AMINO-2-HYDROXYPROPIONIC ACID DERIVATIVES | KANEKA CORPORATION | 2006-06-22 | — | — | US | disclosed |
| US-7057066-B2 | Process for producing 3-amino-2-hydroxypropionic acid derivatives | KANEKA CORPORATION (JP) | 2006-06-06 | — | — | US | disclosed |
| US-20040181074-A1 | Process for producing oxazolidinone derivative of beta-hydroxyethylamine compound and for producing beta-hydroxyethlamine compound | KANEKA CORPORATION (JP) | 2004-09-16 | — | — | US | disclosed |
| EP-1403257-A1 | PROCESSES FOR PRODUCING OXAZOLIDINONE DERIVATIVE OF BETA-HYDROXYETHYLAMINE COMPOUND AND FOR PRODUCING BETA-HYDROXYETHYLAMINE COMPOUND | KANEKA CORPORATION (JP) | 2004-03-31 | — | — | EP | disclosed |
| US-20040049074-A1 | Process for producing 3-amino-2-hydroxypropionic acid derivatives | KANEKA CORPORATION (JP) | 2004-03-11 | — | — | US | disclosed |
| EP-1300391-A1 | PROCESS FOR PRODUCING 3-AMINO-2-HYDROXYPROPIONIC ACID DERIVATIVES | KANEKA CORPORATION (JP) | 2003-04-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040049074-A1 | Process for producing 3-amino-2-hydroxypropionic acid derivatives | AASDHPPT, HPD, HAAO | ALDH1A1 165/4885ALOX15 3183/4885CTSL 2265/4885 |
| US-20060135784-A1 | PROCESS FOR PRODUCING 3-AMINO-2-HYDROXYPROPIONIC ACID DERIVATIVES | AASDHPPT, HPD, HAAO | ALDH1A1 183/4885ALOX15 3200/4885CTSL 2214/4885 |
| US-20040181074-A1 | Process for producing oxazolidinone derivative of beta-hydroxyethylamine compound and for producing beta-hydroxyethlamine compound | HNMT, PNMT, HRH4 | ALDH1A1 1062/4885ALOX15 2616/4885CTSL 3057/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.