Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 5/20 | 0.46 |
| ▸ | HTR1A | P08908 | 6/20 | 0.43 |
| ▸ | HTR1D | P28221 | 4/20 | 0.43 |
| ▸ | HTR1B | P28222 | 4/20 | 0.43 |
| ▸ | RORC | P51449 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.42 |
| ▸ | DRD2 | P14416 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | DDX3X | O00571 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3199702 | 0.95 | DDX3X (0.43) | CCR3HTR1AHTR1DHTR1BRORC | |
| SCHEMBL4722569 | 0.92 | CCR3 (0.48) | CCR3HTR1AHTR1DHTR1BNPSR1 | |
| SCHEMBL3196731 | 0.91 | RORC (0.50) | CCR3HTR1AHTR1DHTR1BRORC | |
| SCHEMBL460041 | 0.88 | DDX3X (0.43) | CCR3HTR1AHTR1DHTR1BRORC | |
| SCHEMBL5330443 | 0.87 | CCR3 (0.44) | CCR3HTR1AHTR1DHTR1BNPSR1 | |
| SCHEMBL4011055 | 0.87 | HTR1A (0.53) | CCR3HTR1ARORCDHODHDRD2 | |
| SCHEMBL401118 | 0.86 | DDX3X (0.42) | CCR3HTR1AHTR1DHTR1BRORC | |
| SCHEMBL4791219 | 0.86 | MAPK10 (0.40) | CCR3HTR1AHTR1DHTR1BRORC | |
| SCHEMBL401741 | 0.85 | ALDH1A1 (0.43) | MAPK8MAPK10SMN1; SMN2DDX3X | |
| SCHEMBL3196716 | 0.84 | NPC1 (0.53) | CCR3HTR1AHTR1DHTR1BRORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070197497-A1 | Compounds, compositions and methods | CYTOKINETICS, INC. | 2007-08-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197497-A1 | Compounds, compositions and methods | TNNI3, TNNC1, TNNT2 | CCR3 4522/4885HTR1A 3992/4885HTR1D 3741/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.