Edetic Acid

Edetic Acid

SCHEMBL566254

O=C([O-])CN(CCN(CC(=O)[O-])CC(=O)[O-])CC(=O)[O-].[Mn+2].[Na+].[Na+]

nearest known ligand 0.73

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Edetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACE known ✓ P12821 1/20 0.48
CA4 known ✓ P22748 8/20 0.40
CA2 known ✓ P00918 4/20 0.35
CA1 known ✓ P00915 4/20 0.35
KDM4E B2RXH2 2/20 0.73
ALOX15 P16050 2/20 0.73
MAPT P10636 1/20 0.73
SMN1; SMN2 Q16637 1/20 0.73
TDP1 Q9NUW8 2/20 0.48
EYA2 O00167 1/20 0.48
APP P05067 1/20 0.48
BLM P54132 2/20 0.46
PMP22 Q01453 2/20 0.46
LMNA P02545 1/20 0.46
CHRM2 P08172 1/20 0.46
ADRA2A P08913 1/20 0.46
TSHR P16473 1/20 0.46
DRD1 P21728 1/20 0.46
SLC6A2 P23975 1/20 0.46
SLC6A4 P31645 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Edetic Acid SCHEMBL28538207 0.97 KDM4E (0.70) KDM4EALOX15MAPTSMN1; SMN2TDP1
Edetic Acid SCHEMBL906 0.97 KDM4E (0.76) KDM4EALOX15MAPTSMN1; SMN2TDP1
Edetic Acid SCHEMBL44287 0.97 KDM4E (0.76) KDM4EALOX15MAPTSMN1; SMN2TDP1
Edetic Acid SCHEMBL42427 0.97 KDM4E (0.76) KDM4EALOX15MAPTSMN1; SMN2TDP1
Edetic Acid SCHEMBL3835316 0.97 KDM4E (0.76) KDM4EALOX15MAPTSMN1; SMN2TDP1
Edetic Acid SCHEMBL548986 0.97 KDM4E (0.68) KDM4EALOX15MAPTSMN1; SMN2TDP1
Edetic Acid SCHEMBL1512919 0.94 KDM4E (0.65) KDM4EALOX15MAPTSMN1; SMN2TDP1
Pentetic Acid SCHEMBL8765357 0.94 KDM4E (0.73) KDM4EALOX15MAPTSMN1; SMN2TDP1
Edetic Acid SCHEMBL1990086 0.94 KDM4E (0.65) KDM4EALOX15MAPTSMN1; SMN2TDP1
Edetic Acid SCHEMBL864972 0.94 KDM4E (0.65) KDM4EALOX15MAPTSMN1; SMN2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118651847-A Carbon dot for zinc ion battery and preparation method thereof 郑州大学 2024-09-17 CN claimed
CN-117352819-A Embedded rocking chair type manganese ion battery 松山湖材料实验室 2024-01-05 CN claimed
CN-116809056-A Preparation method of manganese gadolinium composite catalyst for purifying o-xylene VOCs 南通大学 2023-09-29 CN claimed
CN-115078736-A Homogeneous phase immunoassay kit for Alzheimer's disease 佛山市观迪医疗器械有限公司 2022-09-20 CN claimed
CN-114920602-A Preparation method of environment-friendly nutritional wettable powder 江苏剑牌农化股份有限公司 2022-08-19 CN claimed
CN-113437340-A Positive electrode electrolyte for zinc-manganese flow battery 中国科学院金属研究所 2021-09-24 CN claimed
CN-108329112-B Pesticide fertilizer containing abamectin and preparation method thereof 内蒙古拜克生物有限公司 2021-04-09 CN claimed
CN-106887606-B Peach-shaped Mn2O3preparation method of/C particles 广西大学 2019-12-13 CN claimed
CN-106348873-A Method for preparing microelement liquid water-soluble fertilizer through alga composite graded fermentation 五洲丰农业科技有限公司 2017-01-25 CN claimed
CN-120130320-A Leaf surface blocking and controlling method for reducing heavy metal pollution 沣田宝农业科技有限公司 2025-06-13 CN disclosed
US-20250136488-A1 Extended- and Multimodal-Release Compositions Finoric LLC 2025-05-01 US disclosed
CN-118651847-A Carbon dot for zinc ion battery and preparation method thereof 郑州大学 2024-09-17 CN disclosed
CN-117550703-A Fluid adding device and water purifier 江苏美亚科泽过滤技术有限公司 2024-02-13 CN disclosed
EP-4301716-A1 FERTILIZER PARTICLES COATED WITH A MICRONUTRIENT SOURCE Yara UK Limited (GB) 2024-01-10 EP disclosed
US-20090163449-A1 SULFO-POLYMER POWDER AND SULFO-POLYMER POWDER BLENDS WITH CARRIERS AND/OR ADDITIVES EASTMAN CHEMICAL COMPANY (US) 2009-06-25 US disclosed
EP-2045012-A1 FLUID CATALYTIC CRACKING CATALYST HAVING DESULFURIZING FUNCTIONS, PROCESS FOR PRODUCTION OF THE SAME, AND PROCESS FOR PRODUCTION OF LOW-SULFUR CATALYTICALLY CRACKED GASOLINE WITH THE CATALYST Idemitsu Kosan Co., Ltd. (JP) 2009-04-08 EP disclosed
US-20070092544-A1 Natural insect repellant INT'L ALLY, INC. 2007-04-26 US disclosed
US-20070049496-A1 LIMONENE-CONTAINING HERBICIDE COMPOSITIONS, HERBICIDE CONCENTRATE FORMULATIONS AND METHODS FOR MAKING AND USING SAME FOR ORGANIC PRODUCTION AVENGER PRODUCTS, LLC 2007-03-01 US disclosed
US-5998488-A PREVENT ADSORPTION OF MICROBIOCIDES BY CONTACT LENSES; MIXTURE CONTAINING BORIC ACID, ETHYLENEDIAMINE AND A CYCLODEXTRIN LION CORPORATION (JP) 1999-12-07 US disclosed
US-4013725-A PROCESS FOR PREPARING HYDROPEROXIDE MITSUBISHI GAS CHEMICAL COMPANY, INC. (JA) 1977-03-22 US disclosed