Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Benzene. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 known ✓ | O43570 | 2/20 | 0.35 |
| ▸ | CA2 known ✓ | P00918 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.32 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.32 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL1537955 | 1.00 | MEN1 (0.40) | MEN1ALDH1A1TSHRKMT2ACA12 | |
| Thiosulfuric Acid SCHEMBL5710739 | 0.87 | MEN1 (0.54) | MEN1ALDH1A1TSHRKMT2A | |
| Thiosulfuric Acid SCHEMBL5710744 | 0.87 | — | — | |
| Thiosulfuric Acid SCHEMBL4088 | 0.87 | — | — | |
| Thiosulfuric Acid SCHEMBL11200821 | 0.87 | ALDH1A1 (0.50) | MEN1ALDH1A1TSHRKMT2A | |
| Thiosulfuric Acid SCHEMBL27724216 | 0.87 | ALDH1A1 (0.50) | MEN1ALDH1A1TSHRKMT2A | |
| Thiosulfuric Acid SCHEMBL11787332 | 0.87 | ALDH1A1 (0.50) | MEN1ALDH1A1TSHRKMT2A | |
| Thiosulfuric Acid SCHEMBL3693073 | 0.82 | MEN1 (0.46) | MEN1ALDH1A1TSHRKMT2A | |
| Sulfuric Acid SCHEMBL3859533 | 0.82 | MEN1 (0.46) | MEN1ALDH1A1TSHRKMT2A | |
| Thiosulfuric Acid SCHEMBL3693419 | 0.82 | MEN1 (0.46) | MEN1ALDH1A1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1914559-B | Silver halide color photographic light-sensitive material and color image forming method | FUJI PHOTO FILM CO LTD | 2011-09-21 | — | — | CN | disclosed |
| CN-1667504-B | Silver halide emulsion and silver halide color photographic light-sensitive material | FUJI PHOTO FILM CO LTD | 2010-11-24 | — | — | CN | disclosed |
| CN-101044431-B | Silver halide color photosensitive material and method of processing the same | FUJI PHOTO FILM CO LTD | 2010-05-12 | — | — | CN | disclosed |
| CN-100561336-C | Silver-halide color photoelement and formation method | FUJI PHOTO FILM CO LTD (JP) | 2009-11-18 | — | — | CN | disclosed |
| CN-101167016-A | Silver halide color photographic light-sensitive material | FUJI PHOTO FILM CO LTD (JP) | 2008-04-23 | — | — | CN | disclosed |
| CN-101069128-A | Silver halide color photographic light-sensitive material | FUJIFILM CORP (JP) | 2007-11-07 | — | — | CN | disclosed |
| CN-101048699-A | Silver halide color light-sensitive material | FUJIFILM CORP (JP) | 2007-10-03 | — | — | CN | disclosed |
| CN-101048700-A | Silver halide color photographic light-sensitive material and image forming method | FUJIFILM CORP (JP) | 2007-10-03 | — | — | CN | disclosed |
| CN-101044431-A | Silver halide color photosensitive material and method of processing the same | FUJIFILM CORP (JP) | 2007-09-26 | — | — | CN | disclosed |
| CN-101040219-A | Concentrated composition for silver halide color paper and method of processing | FUJIFILM CORP (JP) | 2007-09-19 | — | — | CN | disclosed |
| CN-1667504-A | Silver halide emulsion and silver halide color photographic light-sensitive material | FUJI PHOTO FILM CO LTD (JP) | 2005-09-14 | — | — | CN | disclosed |
| CN-1648767-A | Diffusion transfer film unit for seal print | FUJI PHOTO FILM CO LTD (JP) | 2005-08-03 | — | — | CN | disclosed |
| CN-1202442-C | Silver halide colour photographic sensitive material | FUJI PHOTO FILM CO LTD (JP) | 2005-05-18 | — | — | CN | disclosed |
| CN-1617045-A | Silver halide color photographic light-sensitive material | FUJI PHOTO FILM CO LTD (JP) | 2005-05-18 | — | — | CN | disclosed |
| CN-1591179-A | Solid bleach-fixing composition for silver halide color photographic light-sensitive material, and method for processing silver halide color photographic light-sensitive material | FUJI PHOTO FILM CO LTD (JP) | 2005-03-09 | — | — | CN | disclosed |
| US-20050008982-A1 | Silver halide color photosensitive material and image forming method | FUJI PHOTO FILM CO., LTD. | 2005-01-13 | — | — | US | disclosed |
| CN-1550886-A | Silver halide colour photosensitive material and imaging method | ��ʿ��Ƭ��ʽ���� | 2004-12-01 | — | — | CN | disclosed |
| CN-1347011-A | Sensitive material packing | FUJI PHOTO FILM CO LTD (JP) | 2002-05-01 | — | — | CN | disclosed |
| CN-1340740-A | Silver halide colour photographic light-sensitive material | FUJI PHOTO FILM CO LTD (JP) | 2002-03-20 | — | — | CN | disclosed |
| CN-1301981-A | Silver halide colour photographic sensitive material | FUJI PHOTO FILM CO LTD (JP) | 2001-07-04 | — | — | CN | disclosed |