Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BBOX1 | O75936 | 2/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | HBB | P68871 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL563942 | 0.90 | GMNN (0.41) | BBOX1GMNNALDH1A1LMNATP53 | |
| SCHEMBL564573 | 0.78 | GMNN (0.50) | BBOX1GMNNALDH1A1LMNATP53 | |
| SCHEMBL4613872 | 0.78 | APP (0.38) | LMNA | |
| SCHEMBL565085 | 0.77 | ALDH1A1 (0.44) | BBOX1GMNNALDH1A1LMNATP53 | |
| SCHEMBL17819132 | 0.77 | ALDH1A1 (0.44) | BBOX1GMNNALDH1A1LMNATP53 | |
| SCHEMBL10484654 | 0.76 | GMNN (0.48) | BBOX1GMNNALDH1A1LMNATP53 | |
| SCHEMBL29623226 | 0.76 | GMNN (0.48) | BBOX1GMNNALDH1A1LMNATP53 | |
| Potassium Ion SCHEMBL10484570 | 0.75 | GMNN (0.46) | BBOX1GMNNALDH1A1LMNATP53 | |
| Potassium Ion SCHEMBL28472448 | 0.72 | ALDH1A1 (0.58) | BBOX1GMNNALDH1A1LMNATP53 | |
| SCHEMBL458345 | 0.71 | APP (0.39) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1651801-A2 | AQUEOUS, ACIDIC SOLUTION AND METHOD FOR ELECTROLYTICALLY DEPOSITING COPPER COATINGS AS WELL AS USE OF SAID SOLUTION | ATOTECH Deutschland GmbH (DE) | 2006-05-03 | — | — | EP | claimed |
| WO-2005014891-A2 | AQUEOUS, ACIDIC SOLUTION AND METHOD FOR ELECTROLYTICALLY DEPOSITING COPPER COATINGS AS WELL AS USE OF SAID SOLUTION | ATOTECH DEUTSCHLAND GMBH (DE) | 2005-02-17 | — | — | WO | claimed |
| EP-1651801-A2 | AQUEOUS, ACIDIC SOLUTION AND METHOD FOR ELECTROLYTICALLY DEPOSITING COPPER COATINGS AS WELL AS USE OF SAID SOLUTION | ATOTECH Deutschland GmbH (DE) | 2006-05-03 | — | — | EP | disclosed |
| WO-2005014891-A2 | AQUEOUS, ACIDIC SOLUTION AND METHOD FOR ELECTROLYTICALLY DEPOSITING COPPER COATINGS AS WELL AS USE OF SAID SOLUTION | ATOTECH DEUTSCHLAND GMBH (DE) | 2005-02-17 | — | — | WO | disclosed |