SCHEMBL5709253

SCHEMBL5709253

C1CCN(CCCCN2CCCC2)C1

nearest known ligand 0.87

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 2/20 0.87
MAPT P10636 1/20 0.62
CYP1A2 P05177 1/20 0.52
MAPK1 P28482 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
SIGMAR1 Q99720 2/20 0.50
CXCR4 P61073 2/20 0.50
CARM1 Q86X55 1/20 0.48
PRMT6 Q96LA8 1/20 0.48
PRMT8 Q9NR22 1/20 0.48
HRH1 P35367 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1882477 0.96 HRH3 (0.93) HRH3MAPTCYP1A2MAPK1SMN1; SMN2
SCHEMBL15462284 0.96 HRH3 (0.93) HRH3MAPTCYP1A2MAPK1SMN1; SMN2
SCHEMBL5665906 0.96 HRH3 (0.93) HRH3MAPTCYP1A2MAPK1SMN1; SMN2
SCHEMBL15762056 0.96 HRH3 (0.93) HRH3MAPTCYP1A2MAPK1SMN1; SMN2
SCHEMBL9371058 0.93 HRH3 (1.00) HRH3MAPTCYP1A2MAPK1SMN1; SMN2
SCHEMBL15933346 0.93 HRH3 (1.00) HRH3MAPTCYP1A2MAPK1SMN1; SMN2
SCHEMBL557955 0.93 HRH3 (1.00) HRH3MAPTCYP1A2MAPK1SMN1; SMN2
SCHEMBL3156252 0.93 HRH3 (1.00) HRH3MAPTCYP1A2MAPK1SMN1; SMN2
SCHEMBL9126300 0.93 HRH3 (1.00) HRH3MAPTCYP1A2MAPK1SMN1; SMN2
SCHEMBL9370421 0.93 HRH3 (1.00) HRH3MAPTCYP1A2MAPK1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023117926-A1 ENVIRONMENTAL ATTRIBUTES FOR NITROGEN CONTAINING CHEMICALS BASF SE (DE) 2023-06-29 WO claimed
EP-3161029-B1 PYRROLIDINE-BASED CATALYSTS FOR USE IN POLYURETHANE MATERIALS HUNTSMAN PETROCHEMICAL LLC (US) 2023-01-11 EP claimed
US-11306008-B2 Working medium and water treatment system KABUSHIKI KAISHA TOSHIBA (JP) 2022-04-19 US claimed
US-20210292194-A1 WORKING MEDIUM AND WATER TREATMENT SYSTEM KABUSHIKI KAISHA TOSHIBA (JP) 2021-09-23 US claimed
CN-106164117-B Pyrrolidine catalysts for polyurethane materials 亨斯迈石油化学有限责任公司 2020-01-17 CN claimed
US-9988483-B2 Pyrrolidine-based catalysts for use in polyurethane materials HUNTSMAN PETROCHEMICAL LLC (US) 2018-06-05 US claimed
EP-3161029-A1 PYRROLIDINE-BASED CATALYSTS FOR USE IN POLYURETHANE MATERIALS Huntsman Petrochemical LLC (US) 2017-05-03 EP claimed
US-20170101501-A1 PYRROLIDINE-BASED CATALYSTS FOR USE IN POLYURETHANE MATERIALS HUNTSMAN PETROCHEMICAL LLC 2017-04-13 US claimed
WO-2015200408-A1 PYRROLIDINE-BASED CATALYSTS FOR USE IN POLYURETHANE MATERIALS HUNTSMAN PETROCHEMICAL LLC (US) 2015-12-30 WO claimed
US-20250084045-A1 PROCESS FOR THE PRODUCTION OF BIS(PYRROLIDINO)BUTANE IN THE LIQUID PHASE BASF SE (DE) 2025-03-13 US disclosed
EP-4412992-A1 PROCESS FOR THE PRODUCTION OF BIS(PYRROLIDINO)BUTANE IN THE LIQUID PHASE BASF SE (DE) 2024-08-14 EP disclosed
US-20240208893-A1 CONTINUOUS PROCESS FOR THE PRODUCTION OF AMINES IN THE GAS PHASE USING A RECYCLE GAS MODE BASF SE (DE) 2024-06-27 US disclosed
US-20240208893-A1 CONTINUOUS PROCESS FOR THE PRODUCTION OF AMINES IN THE GAS PHASE USING A RECYCLE GAS MODE BASF SE (DE) 2024-06-27 US disclosed
CN-118076590-A Method for producing bis (pyrrolidinyl) butane in liquid phase 巴斯夫欧洲公司 2024-05-24 CN disclosed
US-20140018547-A1 Process for Preparing Pyrrolidine BASF SE (DE) 2014-01-16 US disclosed
WO-2014009292-A1 METHOD FOR PRODUCING PYROLLIDINE BASF SE (DE) 2014-01-16 WO disclosed
EP-1108715-B1 Process for dehydration and purification of crude pyrrolidine BASF AG (DE) 2006-11-08 EP disclosed
US-6353118-B1 ONE STEP CONTINUOUS DISTILLATION AT A PRESSURE AT THE TOP OF LESS THAN 950 HPA IN A COLUMN HAVING A STRIPPING SECTION AND A RECTIFYING SECTION BASF AKTIENGESELLSCHAFT (DE) 2002-03-05 US disclosed
EP-1108715-A1 Process for dehydration and purification of crude pyrrolidine BASF AKTIENGESELLSCHAFT (DE) 2001-06-20 EP disclosed
WO-1981001845-A1 PROTON-CATALYSED REACTIONS IN WHICH WATER IS NOT A STOICHIOMETRIC REACTANT CATALYSED BY METAL CATION-EXCHANGED LAYERED CLAYS BRITISH PETROLEUM CO (GB) 1981-07-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250084045-A1 PROCESS FOR THE PRODUCTION OF BIS(PYRROLIDINO)BUTANE IN THE LIQUID PHASE BBOX1, PPOX, POLB HRH3 1342/4885MAPT 1233/4885CYP1A2 519/4885
US-20140018547-A1 Process for Preparing Pyrrolidine SCO2, BBOX1, HMOX2 HRH3 577/4885MAPT 2349/4885CYP1A2 332/4885
US-20240208893-A1 CONTINUOUS PROCESS FOR THE PRODUCTION OF AMINES IN THE GAS PHASE USING A RECYCLE GAS MODE ADH1A, ADH1C, ADH5 HRH3 20/4885MAPT 1584/4885CYP1A2 165/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.