Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | PNLIP | P16233 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | BCL2 | P10415 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | TTR | P02766 | 3/20 | 0.34 |
| ▸ | ESR1 | P03372 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28636154 | 0.78 | MAPT (0.39) | CYP19A1CYP3A4MEN1KMT2ACYP1A1 | |
| SCHEMBL8572826 | 0.78 | CYP19A1 (0.37) | CYP19A1CYP3A4MEN1KMT2ACYP1A1 | |
| SCHEMBL8575536 | 0.75 | CYP19A1 (0.37) | CYP19A1CYP3A4MEN1KMT2ACYP1A1 | |
| SCHEMBL911922 | 0.73 | ALDH1A1 (0.44) | CYP19A1CYP3A4MEN1KMT2ACYP1A1 | |
| SCHEMBL20550365 | 0.72 | MAOA (0.45) | CYP19A1CYP3A4MEN1KMT2ACYP1A1 | |
| SCHEMBL2852450 | 0.72 | PKM (0.42) | CYP19A1CYP3A4MEN1KMT2ACYP2C19 | |
| SCHEMBL3937086 | 0.68 | MAOA (0.41) | CYP19A1CYP3A4MEN1KMT2ACYP1A1 | |
| SCHEMBL29462263 | 0.67 | MET (0.45) | CYP19A1CYP3A4MEN1KMT2ACYP1A1 | |
| SCHEMBL8577569 | 0.66 | ABCG2 (0.42) | CYP19A1CYP3A4CYP2C19CYP2C9MAPT | |
| SCHEMBL27586967 | 0.66 | ALDH1A1 (0.41) | CYP19A1CYP3A4MEN1KMT2ACYP1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2598150-A2 | COMPOSITIONS FOR PROLIFERATION OF CELLS AND RELATED METHODS | The Hospital For Sick Children (CA) | 2013-06-05 | — | — | EP | disclosed |
| WO-2012018643-A2 | COMPOSITIONS FOR PROLIFERATION OF CELLS AND RELATED METHODS | THE HOSPITAL FOR SICK CHILDREN (CA) | 2012-02-09 | — | — | WO | disclosed |