Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
| ▸ | CTSB | P07858 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10964347 | 0.98 | ALDH1A1 (0.35) | ALDH1A1ACHE | |
| SCHEMBL5015274 | 0.90 | — | — | |
| SCHEMBL10498521 | 0.80 | OPRD1 (0.34) | — | |
| SCHEMBL10959047 | 0.80 | ALDH1A1 (0.39) | ALDH1A1ACHE | |
| SCHEMBL3667855 | 0.76 | — | — | |
| SCHEMBL11884623 | 0.74 | — | — | |
| SCHEMBL18343465 | 0.71 | — | — | |
| SCHEMBL10498907 | 0.69 | LMNA (0.41) | ALDH1A1 | |
| SCHEMBL28313076 | 0.68 | FDPS (0.31) | — | |
| SCHEMBL149956 | 0.66 | MAPT (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4501695-A | DIURETIC STEROIDS | THE UPJOHN COMPANY (US) | 1985-02-26 | — | — | US | claimed |
| US-20060063932-A1 | Aminoalkylpyrrolidine serotonin receptor ligands and compositions, their pharmaceutical uses, and methods for their synthesis | RUI YUANJIN | 2006-03-23 | — | — | US | disclosed |
| EP-1339677-B1 | AMINOALKYLPYRROLIDINE SEROTONIN RECEPTOR LIGANDS AND COMPOSITIONS, THEIR PHARMACEUTICAL USES, AND METHODS FOR THEIR SYNTHESIS | WARNER LAMBERT CO (US) | 2006-01-04 | — | — | EP | disclosed |
| US-20040039044-A1 | Aminoalkylpyrrolidine serotonin receptor ligands and compositions, their pharmaceutical uses, and methods for their synthesis | RUI YUANJIN (US) | 2004-02-26 | — | — | US | disclosed |
| EP-1339677-A1 | AMINOALKYLPYRROLIDINE SEROTONIN RECEPTOR LIGANDS AND COMPOSITIONS, THEIR PHARMACEUTICAL USES, AND METHODS FOR THEIR SYNTHESIS | Warner-Lambert Company LLC (US) | 2003-09-03 | — | — | EP | disclosed |
| WO-2002036560-A1 | AMINOALKYLPYRROLIDINE SEROTONIN RECEPTOR LIGANDS AND COMPOSITIONS, THEIR PHARMACEUTICAL USES, AND METHODS FOR THEIR SYNTHESIS | WARNER-LAMBERT COMPANY LLC (US) | 2002-05-10 | — | — | WO | disclosed |
| US-4501695-A | DIURETIC STEROIDS | THE UPJOHN COMPANY (US) | 1985-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060063932-A1 | Aminoalkylpyrrolidine serotonin receptor ligands and compositions, their pharmaceutical uses, and methods for their synthesis | HTR7, HTR5A, HTR1A | ALDH1A1 1159/4885ACHE 409/4885CTSL 391/4885 |
| US-20040039044-A1 | Aminoalkylpyrrolidine serotonin receptor ligands and compositions, their pharmaceutical uses, and methods for their synthesis | HTR7, HTR5A, HTR1A | ALDH1A1 1092/4885ACHE 375/4885CTSL 332/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.