Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GPR52 | Q9Y2T5 | 7/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CLK1 | P49759 | 1/20 | 0.38 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.38 |
| ▸ | WEE1 | P30291 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5738764 | 0.92 | MAOB (0.42) | MAOBKMT2AMEN1GPR52MAPT | |
| SCHEMBL5738604 | 0.83 | MAOB (0.40) | MAOBAKR1C3AKR1C2KMT2AMEN1 | |
| SCHEMBL5739744 | 0.82 | SCD (0.42) | KMT2AMEN1DHODHGPR35 | |
| SCHEMBL5767326 | 0.80 | CCR1 (0.39) | KMT2AMEN1DHODHGPR35 | |
| SCHEMBL5737188 | 0.78 | GPR35 (0.41) | CLK1DHODHGPR35 | |
| SCHEMBL13168625 | 0.69 | MCL1 (0.63) | MAPTDHODH | |
| SCHEMBL5736875 | 0.67 | MAPT (0.41) | KMT2AMEN1MAPT | |
| SCHEMBL1853742 | 0.66 | GPR52 (0.49) | KMT2AMEN1GPR52 | |
| SCHEMBL2610304 | 0.65 | MAOB (0.67) | MAOBKMT2AMEN1GPR52MAPT | |
| SCHEMBL6089789 | 0.65 | PPARG (0.48) | MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1646624-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | Biolipox AB (SE) | 2006-04-19 | — | — | EP | disclosed |
| WO-2005005415-A1 | INDOLES USEFUL IN THE TREATMENT OF INFLAMMATION | BIOLIPOX AB (SE) | 2005-01-20 | — | — | WO | disclosed |