SCHEMBL57389

SCHEMBL57389

COC(=O)c1cc(N)ccc1Cl

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 5/20 0.61
ABL1 P00519 1/20 0.54
MEN1 O00255 5/20 0.53
KMT2A Q03164 5/20 0.53
LMNA P02545 4/20 0.53
SMN1; SMN2 Q16637 2/20 0.53
ALDH1A1 P00352 8/20 0.50
MAPT P10636 5/20 0.50
HTT P42858 2/20 0.50
NPSR1 Q6W5P4 2/20 0.50
TSHR P16473 2/20 0.50
HSD17B10 Q99714 4/20 0.47
KDM4E B2RXH2 4/20 0.47
HPGD P15428 3/20 0.47
GLA P06280 1/20 0.47
CASP1 P29466 1/20 0.47
CASP7 P55210 1/20 0.47
ATM Q13315 1/20 0.47
CFTR P13569 1/20 0.47
NQO2 P16083 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL5389504 0.98 GAA (0.59) GAAABL1MEN1KMT2ALMNA
SCHEMBL145288 0.85 GAA (0.66) GAAABL1ALDH1A1MAPTTSHR
Hydrochloric Acid SCHEMBL3865922 0.84 GAA (0.64) GAAABL1ALDH1A1MAPTTSHR
SCHEMBL1403643 0.82 GAA (0.72) GAAABL1MEN1KMT2ALMNA
SCHEMBL5032667 0.82 GAA (0.41) GAAABL1MEN1KMT2ALMNA
SCHEMBL6168887 0.81 GAA (0.66) GAAABL1MEN1KMT2AALDH1A1
SCHEMBL4363906 0.81 ABL1 (0.62) ABL1MEN1KMT2ALMNASMN1; SMN2
SCHEMBL7623605 0.81 GAA (0.70) GAAABL1MEN1KMT2ALMNA
SCHEMBL9705197 0.81 GAA (0.65) GAAABL1ALDH1A1MAPTTSHR
SCHEMBL24269548 0.81 NR1H4 (0.43) GAAMEN1KMT2ALMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 249 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4229055-B1 COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF CRYPTOSPORIDIOSIS NOVARTIS AG (CH) 2026-03-04 EP disclosed
EP-4666856-A2 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO Corteva Agriscience LLC (US) 2025-12-24 EP disclosed
US-12490741-B2 Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto CORTEVA AGRISCIENCE LLC (US) 2025-12-09 US disclosed
US-20250359552-A1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-11-27 US disclosed
EP-3578543-B1 COMPOSITIONS COMPRISING MOLECULES HAVING PESTICIDAL UTILITY AND PROCESSES RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-08-20 EP disclosed
US-20250134105-A1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-05-01 US disclosed
US-12256738-B2 Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto CORTEVA AGRISCIENCE LLC (US) 2025-03-25 US disclosed
CN-119552166-A PARP1/CDK6 double-target inhibitor and preparation method and application thereof 中国药科大学 2025-03-04 CN disclosed
US-20250008960-A1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO CORTEVA AGRISCIENCE LLC (US) 2025-01-09 US disclosed
US-12018024-B2 Compounds and compositions for the treatment of cryptosporidiosis NOVARTIS AG (CH) 2024-06-25 US disclosed
WO-1996029327-A1 TRYPSIN AND THROMBIN INHIBITORS NOVARTIS AG (CH) 1996-09-26 WO disclosed
EP-0497816-B1 TREATMENT OF HIV INFECTIONS AND COMPOUNDS USEFUL THEREIN UNIROYAL CHEMICAL LTD (CA) 1995-05-17 EP disclosed
US-5382590-A Gastrointestinal disorders and nervous system disorders RHONE-POULENC RORER S.A. (FR) 1995-01-17 US disclosed
EP-0497816-A1 TREATMENT OF HIV INFECTIONS AND COMPOUNDS USEFUL THEREIN. UNIROYAL CHEMICAL LTD (CA) 1992-08-12 EP disclosed
WO-1991012000-A1 ANILINE DERIVATIVES OF α-STYRYL CARBINOLS AS ANTIFUNGAL AGENTS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1991-08-22 WO disclosed
WO-1991005761-A1 TREATMENT OF HIV INFECTIONS AND COMPOUNDS USEFUL THEREIN UNIROYAL CHEMICAL LTD./UNIROYAL CHEMICAL LTEE (CA) 1991-05-02 WO disclosed
US-4439229-A Substituted phthalimides herbicides ROHM AND HAAS COMPANY (US) 1984-03-27 US disclosed
EP-0068822-A2 Novel heterocyclic substituted benzenes, herbicidal compositions containing them and the use thereof for combating weeds ROHM AND HAAS COMPANY (US) 1983-01-05 EP disclosed
US-4104049-A Chlorine-substituted vinylaminobenzoic acid compounds and plant growth regulant compositions BAYER AKTIENGESELLSCHAFT (DE) 1978-08-01 US disclosed
US-4094636-A DIAZOTIZATION HOECHST AKTIENGESELLSCHAFT (DT) 1978-06-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250134105-A1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO ACHE, DDT, MLYCD GAA 880/4885ABL1 2224/4885MEN1 1180/4885
US-12018024-B2 Compounds and compositions for the treatment of cryptosporidiosis SLC10A2, SI, SLC10A1 GAA 831/4885ABL1 562/4885MEN1 1920/4885
US-12256738-B2 Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto ACHE, DDT, MLYCD GAA 880/4885ABL1 2224/4885MEN1 1180/4885
US-20250008960-A1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO ACHE, DDT, MLYCD GAA 880/4885ABL1 2224/4885MEN1 1180/4885
US-20250359552-A1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO ACHE, DDT, MLYCD GAA 880/4885ABL1 2224/4885MEN1 1180/4885
US-12490741-B2 Molecules having pesticidal utility, and intermediates, compositions, and processes, related thereto ACHE, DDT, MLYCD GAA 880/4885ABL1 2224/4885MEN1 1180/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.