Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Dihexylcarbamodithioate Sodium Salt. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 known ✓ | O43570 | 15/20 | 1.00 |
| ▸ | CA1 known ✓ | P00915 | 14/20 | 1.00 |
| ▸ | CA2 known ✓ | P00918 | 13/20 | 1.00 |
| ▸ | CA4 known ✓ | P22748 | 2/20 | 0.54 |
| ▸ | CA9 | Q16790 | 15/20 | 1.00 |
| ▸ | MGLL | Q99685 | 1/20 | 0.55 |
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.54 |
| ▸ | EHMT1 | Q9H9B1 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.46 |
| ▸ | DNM1 | Q05193 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4440849 | 1.00 | CA12 (1.00) | CA12CA9CA1CA2MGLL | |
| SCHEMBL11610877 | 1.00 | CA12 (1.00) | CA12CA9CA1CA2MGLL | |
| SCHEMBL9356067 | 1.00 | CA12 (1.00) | CA12CA9CA1CA2MGLL | |
| SCHEMBL6414649 | 1.00 | CA12 (1.00) | CA12CA9CA1CA2MGLL | |
| SCHEMBL8814695 | 1.00 | CA12 (1.00) | CA12CA9CA1CA2MGLL | |
| SCHEMBL9356073 | 1.00 | CA12 (1.00) | CA12CA9CA1CA2MGLL | |
| SCHEMBL6991048 | 1.00 | CA12 (1.00) | CA12CA9CA1CA2MGLL | |
| SCHEMBL15158003 | 1.00 | CA12 (1.00) | CA12CA9CA1CA2MGLL | |
| SCHEMBL701003 | 0.98 | CA12 (0.95) | CA12CA9CA1CA2MGLL | |
| SCHEMBL8812737 | 0.95 | CA12 (0.91) | CA12CA9CA1CA2MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 98 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3363935-B1 | FIBER FOR RUBBER REINFORCEMENT, RUBBER-FIBER COMPOSITE, AND PNEUMATIC TIRE USING SAME | BRIDGESTONE CORP (JP) | 2025-03-12 | — | — | EP | disclosed |
| WO-2025028496-A1 | METHOD FOR PRODUCING RUBBER COMPOSITION | 株式会社ブリヂストン | 2025-02-06 | — | — | WO | disclosed |
| CN-113631647-B | Sealant rubber composition for inner surface of tire and sealant coated tire | 住友橡胶工业株式会社 | 2023-12-08 | — | — | CN | disclosed |
| WO-2023228463-A1 | METHOD FOR PRODUCING RUBBER COMPOSITION, RUBBER COMPOSITION AND TIRE | 株式会社ブリヂストン | 2023-11-30 | — | — | WO | disclosed |
| EP-3266817-B1 | RUBBER COMPOSITION FOR TIRES, AND TIRE | BRIDGESTONE CORP (JP) | 2023-04-05 | — | — | EP | disclosed |
| WO-2022080133-A1 | RUBBER COMPOSITION FOR TIRE TREAD, AND TIRE | 株式会社ブリヂストン | 2022-04-21 | — | — | WO | disclosed |
| EP-3643517-B1 | PNEUMATIC TIRE | BRIDGESTONE CORP (JP) | 2022-04-13 | — | — | EP | disclosed |
| EP-3936561-A1 | SEALANT RUBBER COMPOSITION FOR INNER TIRE SURFACE AND SEALANT-COATED TIRE | Sumitomo Rubber Industries, Ltd. (JP) | 2022-01-12 | — | — | EP | disclosed |
| CN-113631647-A | Sealant rubber composition for inner surface of tire and sealant-coated tire | 住友橡胶工业株式会社 | 2021-11-09 | — | — | CN | disclosed |
| EP-2716702-B1 | METHOD FOR PRODUCING RUBBER COMPOSITION | BRIDGESTONE CORP (JP) | 2020-11-04 | — | — | EP | disclosed |
| EP-2623553-A1 | METHOD FOR MANUFACTURING RUBBER COMPOSITION | Bridgestone Corporation (JP) | 2013-08-07 | — | — | EP | disclosed |
| EP-2623547-A1 | METHOD FOR MANUFACTURING RUBBER COMPOSITION | Bridgestone Corporation (JP) | 2013-08-07 | — | — | EP | disclosed |
| EP-2623551-A1 | METHOD FOR MANUFACTURING RUBBER COMPOSITION | Bridgestone Corporation (JP) | 2013-08-07 | — | — | EP | disclosed |
| WO-2013050426-A1 | CARBONIC ANHYDRASE INHIBITOR COMPRISING A DITHIOCARBAMATE | UNIVERSITETET I OSLO (NO) | 2013-04-11 | — | — | WO | disclosed |
| US-20060287529-A1 | Solid phase synthesis of antitumoral compounds | PHARMA MAR, S.A.U. (ES) | 2006-12-21 | — | — | US | disclosed |
| EP-1613635-A2 | SOLID PHASE SYNTHESIS OF ANTITUMORAL COMPOUNDS | PHARMA MAR, S.A. (ES) | 2006-01-11 | — | — | EP | disclosed |
| WO-2004073598-A2 | SOLID PHASE SYNTHESIS OF ANTITUMORAL COMPOUNDS | PHARMA MAR, S.A.U. (ES) | 2004-09-02 | — | — | WO | disclosed |
| US-4317758-A | SULFUR CONATING COMPOUNDS DISSOLVED IN A MODIFIED ACRYLAMIDE POLYMER | PHILLIPS PETROLEUM COMPANY (US) | 1982-03-02 | — | — | US | disclosed |
| EP-0039083-A1 | Viscosity-stabilized aqueous acrylamide polymer solutions and use of viscosity stabilizer compounds | PHILLIPS PETROLEUM COMPANY (US) | 1981-11-04 | — | — | EP | disclosed |
| US-4081386-A | ANTIOXIDANTS | THE LUBRIZOL CORPORATION (US) | 1978-03-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060287529-A1 | Solid phase synthesis of antitumoral compounds | TSNAX, TSN, PLIN5 | CA12 3084/4885CA1 2605/4885CA2 3519/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.