SCHEMBL57448

SCHEMBL57448

COC([SiH3])(CNc1ccccc1)OC

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.41
ALDH1A1 P00352 3/20 0.40
TSHR P16473 1/20 0.39
SIGMAR1 Q99720 1/20 0.37
CA2 P00918 2/20 0.37
CA12 O43570 1/20 0.37
CA9 Q16790 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
RAB9A P51151 2/20 0.35
LMNA P02545 1/20 0.35
CYP1A2 P05177 1/20 0.34
CYP3A4 P08684 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
KCNH3 Q9ULD8 1/20 0.34
CA1 P00915 1/20 0.34
HIF1A Q16665 3/20 0.33
HTT P42858 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2157273 0.78 MAPT (0.53) MAPTALDH1A1TSHRCA2CA12
SCHEMBL17700506 0.78 MAPT (0.42) MAPTALDH1A1TSHRSIGMAR1CA2
SCHEMBL978044 0.72 SIGMAR1 (0.41) MAPTALDH1A1TSHRSIGMAR1CA2
SCHEMBL3732806 0.72 MAPT (0.48) MAPTALDH1A1TSHRSIGMAR1CA2
Hydrochloric Acid SCHEMBL17710416 0.70 MAPT (0.46) MAPTALDH1A1TSHRSIGMAR1CA2
SCHEMBL2548915 0.69 MAPT (0.46) MAPTALDH1A1TSHRCA2CA12
SCHEMBL9323396 0.68 ALDH1A1 (0.44) MAPTALDH1A1TSHRSIGMAR1CA2
SCHEMBL11041549 0.68 MAPT (0.44) MAPTALDH1A1TSHRSIGMAR1CA2
SCHEMBL6702352 0.68 TAAR1 (0.46) MAPTALDH1A1TSHRSIGMAR1CA2
SCHEMBL15114128 0.68 MAPT (0.50) MAPTALDH1A1TSHRSIGMAR1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 249 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2026041693-A1 HIGH-SOLIDS TRIGLYCERIDE OIL BASED WOOD COATING COMPOSITIONS SPSV B.V. (NL) 2026-02-26 WO claimed
EP-4700098-A1 HIGH-SOLIDS TRIGLYCERIDE OIL BASED WOOD COATING COMPOSITIONS SPSV B.V. (NL) 2026-02-25 EP claimed
EP-4638540-A1 A METHOD FOR PREPARING A SILANISED POLYURETHANE PREPOLYMER, ITS USE AND A METHOD FOR PRODUCING A MOISTURE-CURED SILANISED ONE-COMPONENT FOAM PCC ROKITA Spolka Akcyjna (PL) 2025-10-29 EP claimed
WO-2024136687-A1 A METHOD FOR PREPARING A SILANISED POLYURETHANE PREPOLYMER, ITS USE AND A METHOD FOR PRODUCING A MOISTURE-CURED SILANISED ONE-COMPONENT FOAM PCC ROKITA SPÓŁKA AKCYJNA (PL) 2024-06-27 WO claimed
EP-3157970-A1 SILYLATED POLYURETHANES Huntsman International LLC (US) 2017-04-26 EP claimed
WO-2015193146-A1 SILYLATED POLYURETHANES HUNTSMAN INTERNATIONAL LLC (US) 2015-12-23 WO claimed
US-20110198030-A1 POLYURETHANE COMPOSITION THAT CONTAINS ALPHA-SILANE AND THAT HAS ANISOTROPIC MATERIAL PROPERTIES SIKA TECHNOLOGY AG (CH) 2011-08-18 US claimed
EP-2189485-B1 Polyurethane composition comprising alpha-silane having anisostropic material properties SIKA TECHNOLOGY AG (CH) 2011-02-16 EP claimed
EP-2189485-A1 Polyurethane composition comprising alpha-silane having anisostropic material properties Sika Technology AG (CH) 2010-05-26 EP claimed
WO-2010049518-A1 POLYURETHANE COMPOSITION THAT CONTAINS ALPHA-SILANE AND HAS ANISOTROPIC MATERIAL PROPERTIES SIKA TECHNOLOGY AG (CH) 2010-05-06 WO claimed
US-20260125587-A1 PROCESS FOR PRODUCING A STORAGE-STABLE ACTIVATOR FOR GLASS AND CERAMIC SUBSTRATES SIKA TECHNOLOGY AG (CH) 2026-05-07 US disclosed
EP-4700098-A1 HIGH-SOLIDS TRIGLYCERIDE OIL BASED WOOD COATING COMPOSITIONS SPSV B.V. (NL) 2026-02-25 EP disclosed
US-12391853-B2 Adhesive formulations for roofing applications and related methods BMIC LLC (US) 2025-08-19 US disclosed
US-20250206871-A1 COATING PRIMER HAVING GOOD APPLICABILITY AT LOW TEMPERATURES SIKA TECHNOLOGY AG (CH) 2025-06-26 US disclosed
EP-4574865-A1 COATING PRIMER HAVING GOOD APPLICABILITY AT LOW TEMPERATURES Sika Technology AG (CH) 2025-06-25 EP disclosed
EP-1613691-A1 EXPANSIBLE MIXTURES DEVOID OF ISOCYANATES EXHIBITING IMPROVED FIRE BEHAVIOUR Consortium für elektrochemische Industrie GmbH (DE) 2006-01-11 EP disclosed
EP-1585778-A1 HYDROPHOBIC PROPELLANT GAS MIXTURES FOR PRODUCING INSULATING FOAMS RATHOR AG (CH) 2005-10-19 EP disclosed
WO-2005049684-A1 POLYURETHANE COMPOSITIONS WITH NCO AND SILYL REACTIVITY HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 2005-06-02 WO disclosed
WO-2004092259-A1 EXPANSIBLE MIXTURES DEVOID OF ISOCYANATES EXHIBITING IMPROVED FIRE BEHAVIOUR Consortium für elektrochemische Industrie GmbH (DE) 2004-10-28 WO disclosed
WO-2004065448-A1 HYDROPHOBIC PROPELLANT GAS MIXTURES FOR PRODUCING INSULATING FOAMS RATHOR AG (CH) 2004-08-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260125587-A1 PROCESS FOR PRODUCING A STORAGE-STABLE ACTIVATOR FOR GLASS AND CERAMIC SUBSTRATES CD40LG, CDH1, VCAM1 MAPT 498/4885ALDH1A1 435/4885TSHR 2279/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.