SCHEMBL574940

SCHEMBL574940

CC(C)CCCCCCCCCCCCCCC(=O)OC(CO)COCC(O)CO

nearest known ligand 0.54

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PRKCA P17252 5/20 0.54
PRKCE Q02156 2/20 0.54
PRKCQ Q04759 2/20 0.54
PRKCD Q05655 2/20 0.54
MAPT P10636 1/20 0.53
MAPK1 P28482 1/20 0.53
LMNA P02545 4/20 0.49
KDM4E B2RXH2 1/20 0.49
DUSP3 P51452 1/20 0.49
MEN1 O00255 1/20 0.49
KMT2A Q03164 1/20 0.49
ALDH1A1 P00352 1/20 0.43
DGKA P23743 1/20 0.43
S1PR1 P21453 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28225640 0.87 MAPT (0.71) PRKCAPRKCEPRKCQPRKCDMAPT
SCHEMBL3453977 0.87 MAPT (0.71) PRKCAPRKCEPRKCQPRKCDMAPT
SCHEMBL574913 0.86 PRKCA (0.69) PRKCAPRKCEPRKCQPRKCDMAPT
SCHEMBL28756217 0.83 MAPT (0.68) PRKCAPRKCEPRKCQPRKCDMAPT
SCHEMBL7109203 0.83 MAPT (0.68) PRKCAPRKCEPRKCQPRKCDMAPT
SCHEMBL29356774 0.83 KDM4E (0.63) PRKCAPRKCEPRKCQPRKCDMAPT
SCHEMBL2703002 0.82 PRKCA (0.72) PRKCAPRKCEPRKCQPRKCDMAPT
SCHEMBL5155403 0.82 PRKCA (0.72) PRKCAPRKCEPRKCQPRKCDMAPT
SCHEMBL20202521 0.82 MAPT (0.68) PRKCAPRKCEPRKCQPRKCDMAPT
SCHEMBL29363445 0.82 LMNA (0.60) PRKCAPRKCEPRKCQPRKCDMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220008319-A1 HAIR COSMETIC AND HAIR TREATMENT METHOD USING SAME SHISEIDO COMPANY, LTD. (JP) 2022-01-13 US disclosed
EP-3875153-A1 HAIR COSMETIC AND HAIR TREATMENT METHOD USING SAME Shiseido Company, Ltd. (JP) 2021-09-08 EP disclosed
US-9839588-B2 Skin external preparation comprising an aqueous dispersion of finely dispersed wax, nonionic surfactant, and ionic water-soluble thickener SHISEIDO COMPANY, LTD. (JP) 2017-12-12 US disclosed
US-20120189675-A1 Skin External Preparations SHISEIDO COMPANY, LTD. (JP) 2012-07-26 US disclosed
EP-2415459-A1 EXTERNAL PREPARATION FOR SKIN Shiseido Company, Ltd. (JP) 2012-02-08 EP disclosed
US-20100316581-A1 Skin External Preparations SHISEIDO COMPANY, LTD. (JP) 2010-12-16 US disclosed
EP-2233154-A1 SKIN EXTERNAL PREPARATION Shiseido Company, Ltd. (JP) 2010-09-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120189675-A1 Skin External Preparations CUTA, KRT18, CD69 PRKCA 1998/4885PRKCE 837/4885PRKCQ 1216/4885
US-20220008319-A1 HAIR COSMETIC AND HAIR TREATMENT METHOD USING SAME SGMS1, POLR1C, SGMS2 PRKCA 3608/4885PRKCE 3460/4885PRKCQ 3883/4885
US-20100316581-A1 Skin External Preparations CUTA, RBP4, TTPA PRKCA 2828/4885PRKCE 2891/4885PRKCQ 2957/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.