Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 8/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 3/20 | 0.42 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 2/20 | 0.41 |
| ▸ | ADAM10 | O14672 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | MMP14 | P50281 | 1/20 | 0.40 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.40 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.40 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5754509 | 0.85 | ITGB3 (0.46) | ITGB3ITGA2BALDH1A1MMP2MEN1 | |
| SCHEMBL5756033 | 0.85 | LDHA (0.43) | ITGB3ITGA2BALDH1A1ITGB1MAPT | |
| SCHEMBL6976528 | 0.80 | ALDH1A1 (0.42) | ALDH1A1MMP2ADAMTS5MEN1CYP2C9 | |
| SCHEMBL5756506 | 0.78 | MMP1 (0.44) | ALDH1A1MMP2MMP9ADAM10MMP1 | |
| SCHEMBL13383344 | 0.72 | MAPT (0.57) | ITGB3ITGA2BMMP2MMP9POLB | |
| SCHEMBL5754622 | 0.72 | LDHA (0.47) | ITGB3ITGA2BMMP2MEN1CYP2C9 | |
| SCHEMBL6976531 | 0.72 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2APOLBMAPT | |
| SCHEMBL5757446 | 0.72 | LDHA (0.47) | ITGB3ITGA2BMMP2MEN1CYP2C9 | |
| SCHEMBL5756354 | 0.70 | MAPT (0.40) | ITGB3ITGA2BALDH1A1MMP2MEN1 | |
| SCHEMBL7945731 | 0.70 | MMP2 (0.57) | MMP2ADAMTS5KMT2AMMP9ADAM10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1208092-B1 | SULFONAMIDE DERIVATIVE AS A MATRIX METALLOPROTEINASE INHIBITOR | SAMSUNG ELECTRONICS CO LTD (KR) | 2006-06-21 | — | — | EP | disclosed |
| US-6548667-B2 | For prevention and treatment of diseases caused by overexpression and overactivation of matrix metalloproteinase | SAMSUNG ELECTRONICS CO. LTD. (KR) | 2003-04-15 | — | — | US | disclosed |
| US-20020169314-A1 | Sulfonamide derivative as a matrix metalloproteinase inhibitor | SAMSUNG ELECTRONICS CO. LTD. (KR) | 2002-11-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020169314-A1 | Sulfonamide derivative as a matrix metalloproteinase inhibitor | MMP9, MMP3, MMP14 | ITGB3 4333/4885ITGA2B 3545/4885ALDH1A1 311/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.