Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.38 |
| ▸ | REN | P00797 | 10/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CKS1B | P61024 | 1/20 | 0.34 |
| ▸ | SKP1 | P63208 | 1/20 | 0.34 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 3/20 | 0.34 |
| ▸ | ACACA | Q13085 | 3/20 | 0.34 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5752071 | 0.92 | ACHE (0.37) | GPR119RENKLK5ACHEBACE1 | |
| SCHEMBL5756949 | 0.82 | REN (0.37) | RENKLK5 | |
| SCHEMBL5758658 | 0.81 | CCR1 (0.34) | CHRM4 | |
| SCHEMBL5757640 | 0.78 | HSD17B10 (0.40) | GPR119 | |
| SCHEMBL5754577 | 0.77 | REN (0.39) | RENKLK5 | |
| SCHEMBL5756667 | 0.76 | REN (0.38) | REN | |
| SCHEMBL5758360 | 0.76 | PSMB1 (0.45) | REN | |
| SCHEMBL5754117 | 0.75 | CACNA1B (0.42) | RENKLK5 | |
| SCHEMBL5759013 | 0.74 | GRN (0.36) | RENACACB | |
| SCHEMBL5754050 | 0.72 | NPC1 (0.37) | REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0997147-B1 | AMINO ACID DERIVATIVES | ONO PHARMACEUTICAL CO (JP) | 2006-03-15 | — | — | EP | claimed |