SCHEMBL5772420

SCHEMBL5772420

CCCC[Sn](CCCC)(CCCC)c1sccc1C

nearest known ligand 0.34

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.34
LMNA P02545 2/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
KDM4E B2RXH2 1/20 0.34
CYP1A2 P05177 1/20 0.33
GAA P10253 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
GSK3B P49841 1/20 0.31
NPC1 O15118 1/20 0.31
PKM P14618 1/20 0.31
RAB9A P51151 1/20 0.31
ATM Q13315 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15168859 0.81
SCHEMBL26106213 0.81 KAT2B (0.32)
SCHEMBL31423181 0.79 HTR7 (0.30)
SCHEMBL19554677 0.77 LMNA (0.34) ALDH1A1LMNAMEN1KMT2AGAA
SCHEMBL8305000 0.77 KEAP1 (0.41) KMT2A
SCHEMBL1685272 0.75 LIPG (0.38) ALDH1A1LMNAMEN1KMT2AKDM4E
SCHEMBL2566044 0.75 LIPG (0.38) ALDH1A1LMNAMEN1KMT2AKDM4E
SCHEMBL8075810 0.75 CYP2A6 (0.32)
SCHEMBL320882 0.75 LIPG (0.38) ALDH1A1LMNAMEN1KMT2AKDM4E
SCHEMBL6047203 0.74 PTGS2 (0.38) ALDH1A1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12435100-B2 Perovskite solar cells PURDUE RESEARCH FOUNDATION (US) 2025-10-07 US disclosed
US-11800784-B2 Two-dimensional halide perovskite materials PURDUE RESEARCH FOUNDATION (US) 2023-10-24 US disclosed
US-20220246865-A1 PEROVSKITE SOLAR CELLS PURDUE RESEARCH FOUNDATION (US) 2022-08-04 US disclosed
US-20210343948-A1 Two-Dimensional Halide Perovskite Materials PURDUE RESEARCH FOUNDATION (US) 2021-11-04 US disclosed
US-10618889-B2 Thiophene monoamine based organic-inorganic hybrid perovskites PURDUE RESEARCH FOUNDATION (US) 2020-04-14 US disclosed
US-20200062740-A1 THIOPHENE MONOAMINE BASED ORGANIC-INORGANIC HYBRID PEROVSKITES PURDUE RESEARCH FOUNDATION (US) 2020-02-27 US disclosed
US-7144913-B2 Dihydropyrrolo[1,2-a]indole and tetrahydropyrido[1,2-a]-indole derivatives as prostaglandin d2 receptor antagonists MERCK FROSST CANADA & CO. (CA) 2006-12-05 US disclosed
EP-1395590-B1 DIHYDROPYRROLO¬1,2-A|INDOLE AND TETRAHYDROPYRIDO¬1,2-A|INDOLE DERIVATIVES AS PROSTAGLANDIN D2 RECEPTOR ANTAGONISTS MERCK FROSST CANADA INC (CA) 2006-09-27 EP disclosed
US-20040180934-A1 Dihydropyrrolo[1,2-a]indole and tetrahydropyrido[1,2-a]-indole derivatives as prostaglandin d2 receptor antagonists MERCK FROSST CANADA LTD. (CA) 2004-09-16 US disclosed
EP-1395590-A2 DIHYDROPYRROLO[1,2-A]INDOLE AND TETRAHYDROPYRIDO[1,2-A]INDOLE DERIVATIVES AS PROSTAGLANDIN D2 RECEPTOR ANTAGONISTS Merck Frosst Canada & Co. (CA) 2004-03-10 EP disclosed
WO-2002094830-A2 DIHYDROPYRROLO[1,2-A]INDOLE AND TETRAHYDROPYRIDO[1,2-a]-INDOLE DERIVATIVES AS PROSTAGLANDIN D2 RECEPTOR ANTAGONISTS MERCK FROSST CANADA & CO. (CA) 2002-11-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10618889-B2 Thiophene monoamine based organic-inorganic hybrid perovskites COMT, TYR, SLC6A3 ALDH1A1 751/4885LMNA 4797/4885MEN1 1578/4885
US-20210343948-A1 Two-Dimensional Halide Perovskite Materials EYA2, BRAP, EYA3 ALDH1A1 2678/4885LMNA 2838/4885MEN1 1450/4885
US-20040180934-A1 Dihydropyrrolo[1,2-a]indole and tetrahydropyrido[1,2-a]-indole derivatives as prostaglandin d2 receptor antagonists PTGDR, PTGDR2, PTGIR ALDH1A1 860/4885LMNA 4685/4885MEN1 3859/4885
US-20220246865-A1 PEROVSKITE SOLAR CELLS BCL3, MCL1, ANXA3 ALDH1A1 2526/4885LMNA 1735/4885MEN1 390/4885
US-12435100-B2 Perovskite solar cells BCL3, MCL1, ANXA3 ALDH1A1 2526/4885LMNA 1735/4885MEN1 390/4885
US-11800784-B2 Two-dimensional halide perovskite materials EYA2, BRAP, EYA3 ALDH1A1 2678/4885LMNA 2838/4885MEN1 1450/4885
US-20200062740-A1 THIOPHENE MONOAMINE BASED ORGANIC-INORGANIC HYBRID PEROVSKITES COMT, TYR, SLC6A3 ALDH1A1 751/4885LMNA 4797/4885MEN1 1578/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.