SCHEMBL5777962

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5819549	0.88	TGFBR1 (0.55)	ALDH1A1MAPTCYP1A2CYP2D6CYP2C19
	SCHEMBL5812694	0.86	TGFBR1 (0.59)	ALDH1A1MAPTCYP1A2CYP2D6CYP2C19
	SCHEMBL5780175	0.85	ADORA2A (0.36)	ALDH1A1MAPTCYP1A2CYP2D6CYP2C19
	SCHEMBL15653814	0.80	CDK4 (0.50)	ALDH1A1MAPTKDM4EGAAMAPK1
	SCHEMBL27997668	0.78	AURKA (0.50)	MAPTKDM4ESMN1; SMN2MEN1KMT2A
	SCHEMBL5781568	0.78	KMT2A (0.47)	MAPTKMT2A
	SCHEMBL24760755	0.78	ALDH1A1 (0.59)	ALDH1A1MAPTCYP1A2CYP2D6CYP2C19
	SCHEMBL5779376	0.77	ALDH1A1 (0.55)	ALDH1A1MAPTCYP1A2CYP2D6CYP2C19
	SCHEMBL6840009	0.76	MEN1 (0.41)	ALDH1A1MAPTMEN1KMT2APKM
	SCHEMBL5822172	0.74	PTGS2 (0.41)	TGFBR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.