SCHEMBL578290

SCHEMBL578290

COc1ccc(N(c2ccc(OC)cc2)c2ccc(N(c3ccc(OC)cc3)c3ccc(OCCCOS(C)(=O)=O)cc3)cc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.48
MAPT P10636 2/20 0.47
HPGD P15428 1/20 0.47
ATM Q13315 1/20 0.47
APLNR P35414 1/20 0.44
ALDH1A1 P00352 4/20 0.41
LMNA P02545 3/20 0.41
NPC1 O15118 2/20 0.41
PTPN1 P18031 1/20 0.41
TSHR P16473 4/20 0.41
KDM4E B2RXH2 1/20 0.41
USP2 O75604 1/20 0.41
MMP9 P14780 1/20 0.41
ALOX15 P16050 1/20 0.41
HTT P42858 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA7 P43166 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17501637 0.91 MAPT (0.50) L3MBTL1MAPTHPGDATMAPLNR
SCHEMBL8943762 0.85 MAPT (0.54) L3MBTL1MAPTHPGDATMALDH1A1
SCHEMBL6277239 0.82 L3MBTL1 (0.49) L3MBTL1MAPTHPGDATMAPLNR
SCHEMBL8944313 0.80 AHR (0.53) L3MBTL1MAPTHPGDATMTSHR
SCHEMBL8943807 0.80 AHR (0.53) L3MBTL1MAPTHPGDATMTSHR
SCHEMBL8943774 0.79 L3MBTL1 (0.57) L3MBTL1MAPTHPGDATMALDH1A1
SCHEMBL8943677 0.79 ACHE (0.54) L3MBTL1MAPTHPGDATMALDH1A1
SCHEMBL8944174 0.77 NR5A1 (0.55) L3MBTL1MAPTHPGDATMLMNA
SCHEMBL8944354 0.77 TSHR (0.49) L3MBTL1MAPTHPGDATMALDH1A1
SCHEMBL24041808 0.76 APLNR (0.47) APLNRALDH1A1LMNATSHRHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8846978-B2 Electronic devices comprising novel phosphonic acid surface modifiers IMPERIAL INNOVATIONS LTD. (GB) 2014-09-30 US disclosed
US-8846978-B2 Electronic devices comprising novel phosphonic acid surface modifiers IMPERIAL INNOVATIONS LTD. (GB) 2014-09-30 US disclosed
US-8586208-B2 Stable electrodes with modified work functions and methods for organic electronic devices GEORGIA TECH RESEARCH CORPORATION (US) 2013-11-19 US disclosed
US-20120114974-A1 ELECTRONIC DEVICES COMPRISING NOVEL PHOSPHONIC ACID SURFACE MODIFIERS NATIONAL SCIENCE FOUNDATION 2012-05-10 US disclosed
EP-2417142-A1 ELECTRONIC DEVICES COMPRISING NOVEL PHOSPHONIC ACID SURFACE MODIFIERS Georgia Tech Research Corporation (US) 2012-02-15 EP disclosed
US-20110114935-A1 Stable electrodes with modified work functions and methods for organic electronic devices GEORGIA TECH RESEARCH CORPORATION (US) 2011-05-19 US disclosed
EP-2304820-A1 STABLE ELECTRODES WITH MODIFIED WORK FUNCTIONS AND METHODS FOR ORGANIC ELECTRONIC DEVICES Georgia Tech Research Corporation (US) 2011-04-06 EP disclosed
WO-2010115854-A1 ELECTRONIC DEVICES COMPRISING NOVEL PHOSPHONIC ACID SURFACE MODIFIERS GEORGIA TECH RESEARCH CORPORATION (US) 2010-10-14 WO disclosed
WO-2010007081-A1 STABLE ELECTRODES WITH MODIFIED WORK FUNCTIONS AND METHODS FOR ORGANIC ELECTRONIC DEVICES GEORGIA TECH RESEARCH CORPORATION (US) 2010-01-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110114935-A1 Stable electrodes with modified work functions and methods for organic electronic devices EPCAM, EMD, L1CAM L3MBTL1 1096/4885MAPT 2192/4885HPGD 3483/4885
US-20120114974-A1 ELECTRONIC DEVICES COMPRISING NOVEL PHOSPHONIC ACID SURFACE MODIFIERS EFNA1, PHOSPHO1, EPHA6 L3MBTL1 1793/4885MAPT 3620/4885HPGD 4387/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.