Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | LPL | P06858 | 12/20 | 0.47 |
| ▸ | LIPG | Q9Y5X9 | 12/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA3 | P07451 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.41 |
| ▸ | F11 | P03951 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3136657 | 0.98 | HIF1A (0.49) | HIF1ALPLLIPGCA1CA2 | |
| SCHEMBL3708268 | 0.95 | LPL (0.49) | HIF1ALPLLIPGCA1CA2 | |
| SCHEMBL16112310 | 0.91 | LPL (0.52) | HIF1ALPLLIPGCA1CA2 | |
| SCHEMBL14804365 | 0.91 | LPL (0.52) | HIF1ALPLLIPGCA1CA2 | |
| SCHEMBL31222864 | 0.85 | SLC18A3 (0.54) | HIF1ALPLLIPG | |
| SCHEMBL2018524 | 0.85 | LPL (0.46) | HIF1ALPLLIPGCA1CA2 | |
| SCHEMBL20428742 | 0.85 | ESR2 (0.49) | HIF1ALPLLIPGCA1CA2 | |
| SCHEMBL14804355 | 0.84 | LPL (0.49) | HIF1ALPLLIPGCA1CA2 | |
| SCHEMBL1983558 | 0.84 | HIF1A (0.42) | HIF1ALPLLIPGCA1CA2 | |
| SCHEMBL31222936 | 0.84 | SLC18A3 (0.51) | HIF1ALPLLIPG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230391779-A1 | BICYCLIC COMPOUNDS, COMPOSITIONS AND USE THEREOF | BETTA PHARMACEUTICALS CO., LTD. (CN) | 2023-12-07 | — | — | US | disclosed |
| EP-4196480-A1 | BICYCLIC COMPOUNDS, COMPOSITIONS AND USE THEREOF | Betta Pharmaceuticals Co., Ltd (CN) | 2023-06-21 | — | — | EP | disclosed |
| US-11572332-B2 | Compound, light-emitting device, light-emitting apparatus, electronic device, and lighting device | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2023-02-07 | — | — | US | disclosed |
| US-11572332-B2 | Compound, light-emitting device, light-emitting apparatus, electronic device, and lighting device | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2023-02-07 | — | — | US | disclosed |
| CN-112441931-A | Compound, light-emitting device, light-emitting apparatus, electronic device, and lighting apparatus | 株式会社半导体能源研究所 | 2021-03-05 | — | — | CN | disclosed |
| US-20210061753-A1 | COMPOUND, LIGHT-EMITTING DEVICE, LIGHT-EMITTING APPARATUS, ELECTRONIC DEVICE, AND LIGHTING DEVICE | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2021-03-04 | — | — | US | disclosed |
| US-20210061753-A1 | COMPOUND, LIGHT-EMITTING DEVICE, LIGHT-EMITTING APPARATUS, ELECTRONIC DEVICE, AND LIGHTING DEVICE | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2021-03-04 | — | — | US | disclosed |
| US-20210043840-A1 | LIGHT-EMITTING ELEMENT, DISPLAY DEVICE, ELECTRONIC DEVICE, ORGANIC COMPOUND, AND LIGHTING DEVICE | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2021-02-11 | — | — | US | disclosed |
| CN-111954939-A | Light-emitting element, display device, electronic device, organic compound, and lighting device | 株式会社半导体能源研究所 | 2020-11-17 | — | — | CN | disclosed |
| EP-2887807-B1 | BENZIMIDAZOLE HEXAHYDROFURO[3,2-B]FURAN DERIVATIVES USEFUL AS AMP-ACTIVATED PROTEIN KINASE ACTIVATORS | MERCK SHARP & DOHME (US) | 2019-09-18 | — | — | EP | disclosed |
| EP-3022210-B1 | NEW AZABENZIMIDAZOLE DERIVATIVES | BOEHRINGER INGELHEIM INT (DE) | 2018-02-21 | — | — | EP | disclosed |
| US-20170334918-A1 | BMP Inhibitors and Methods of Use Thereof | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. | 2017-11-23 | — | — | US | disclosed |
| US-9682983-B2 | BMP inhibitors and methods of use thereof | THE BRIGHAM AND WOMEN'S HOSPITAL, INC. (US) | 2017-06-20 | — | — | US | disclosed |
| US-9453025-B2 | Tricyclic compounds and PBK inhibitors containing the same | ONCOTHERAPY SCIENCE, INC. (JP) | 2016-09-27 | — | — | US | disclosed |
| US-20160046633-A1 | BMP INHIBITORS AND METHODS OF USE THEREOF | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES | 2016-02-18 | — | — | US | disclosed |
| US-20150183799-A1 | Tricyclic Compounds and PBK Inhibitors Containing the Same | ONCOTHERAPY SCIENCE INC (JP) | 2015-07-02 | — | — | US | disclosed |
| US-8962648-B2 | Tricyclic compounds and PBK inhibitors containing the same | ONCOTHERAPY SCIENCE, INC. (JP) | 2015-02-24 | — | — | US | disclosed |
| US-20130178459-A1 | TRICYCLIC COMPOUNDS AND PBK INHIBITORS CONTAINING THE SAME | ONCOTHERAPY SCIENCE, INC. (JP) | 2013-07-11 | — | — | US | disclosed |
| WO-2010107768-A1 | BICYCLIC COMPOUNDS AS INHIBITORS OF DIACYLGLYCEROL ACYLTRANSFERASE | SCHERING CORPORATION (US) | 2010-09-23 | — | — | WO | disclosed |
| WO-2006120349-A1 | NOVEL PHENYL-PYRIDINYL-PIPERAZINE DERIVATIVES, A METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID DERIVATIVES | LES LABORATOIRES SERVIER (FR) | 2006-11-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230391779-A1 | BICYCLIC COMPOUNDS, COMPOSITIONS AND USE THEREOF | CYP11B2, CYP11B1, CYP27A1 | HIF1A 584/4885LPL 3471/4885LIPG 3168/4885 |
| US-20210043840-A1 | LIGHT-EMITTING ELEMENT, DISPLAY DEVICE, ELECTRONIC DEVICE, ORGANIC COMPOUND, AND LIGHTING DEVICE | DDT, TRPA1, MAP1LC3A | HIF1A 4568/4885LPL 527/4885LIPG 860/4885 |
| US-11572332-B2 | Compound, light-emitting device, light-emitting apparatus, electronic device, and lighting device | ARL1, CRY1, MCOLN1 | HIF1A 2507/4885LPL 1246/4885LIPG 2344/4885 |
| US-20130178459-A1 | TRICYCLIC COMPOUNDS AND PBK INHIBITORS CONTAINING THE SAME | PBDC1, SBK1, PLK2 | HIF1A 4423/4885LPL 4071/4885LIPG 3497/4885 |
| US-20160046633-A1 | BMP INHIBITORS AND METHODS OF USE THEREOF | BMP1, BMPR2, BMP2 | HIF1A 308/4885LPL 156/4885LIPG 91/4885 |
| US-20170334918-A1 | BMP Inhibitors and Methods of Use Thereof | BMP1, BMPR2, BMP2 | HIF1A 308/4885LPL 156/4885LIPG 91/4885 |
| US-20210061753-A1 | COMPOUND, LIGHT-EMITTING DEVICE, LIGHT-EMITTING APPARATUS, ELECTRONIC DEVICE, AND LIGHTING DEVICE | ARL1, CRY1, MCOLN1 | HIF1A 2507/4885LPL 1246/4885LIPG 2344/4885 |
| US-20150183799-A1 | Tricyclic Compounds and PBK Inhibitors Containing the Same | PBDC1, SBK1, PLK2 | HIF1A 4423/4885LPL 4071/4885LIPG 3497/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.