Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.65 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.39 |
| ▸ | UBE2M | P61081 | 1/20 | 0.39 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL291054 | 1.00 | TRPM8 (0.65) | TRPM8EPHX1KMT2ASERPINE1MEN1 | |
| SCHEMBL31438756 | 1.00 | TRPM8 (0.65) | TRPM8EPHX1KMT2ASERPINE1MEN1 | |
| SCHEMBL16551709 | 1.00 | TRPM8 (0.65) | TRPM8EPHX1KMT2ASERPINE1MEN1 | |
| SCHEMBL4127806 | 1.00 | TRPM8 (0.65) | TRPM8EPHX1KMT2ASERPINE1MEN1 | |
| SCHEMBL16004827 | 1.00 | TRPM8 (0.65) | TRPM8EPHX1KMT2ASERPINE1MEN1 | |
| SCHEMBL3219019 | 1.00 | TRPM8 (0.65) | TRPM8EPHX1KMT2ASERPINE1MEN1 | |
| SCHEMBL10044268 | 1.00 | TRPM8 (0.65) | TRPM8EPHX1KMT2ASERPINE1MEN1 | |
| SCHEMBL16551708 | 1.00 | TRPM8 (0.65) | TRPM8EPHX1KMT2ASERPINE1MEN1 | |
| SCHEMBL18812290 | 0.89 | TRPM8 (0.62) | TRPM8EPHX1KMT2ASERPINE1MEN1 | |
| SCHEMBL2628763 | 0.86 | TRPM8 (0.70) | TRPM8EPHX1KMT2ASERPINE1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 306 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122028893-A | Composition and method for producing the same | 奇华顿股份有限公司 | 2026-05-12 | — | — | CN | claimed |
| US-12600751-B2 | Modified S2 subunit of the coronavirus spike protein | BOEHRINGER INGELHEIM VETMEDICA GMBH (DE) | 2026-04-14 | — | — | US | claimed |
| EP-4599698-A1 | PRODUCTS COMPRISING SENSORY AGENTS | Nicoventures Trading Limited (GB) | 2025-08-13 | — | — | EP | claimed |
| US-20240197222-A1 | ORAL CARE FLAVOUR FOR IMPROVING HAPPINESS STATE AND METHOD OF ASSESSING | GIVAUDAN SA (CH) | 2024-06-20 | — | — | US | claimed |
| US-20240197183-A1 | ORAL CARE FLAVOUR FOR IMPROVING INVIGORATION STATE AND METHOD OF ASSESSING | GIVAUDAN SA (CH) | 2024-06-20 | — | — | US | claimed |
| US-11999766-B2 | Modified S1 subunit of the coronavirus spike protein | BOEHRINGER INGELHEIM VETMEDIA GMBH (DE) | 2024-06-04 | — | — | US | claimed |
| EP-4347761-A1 | ORAL CARE FLAVOUR FOR IMPROVING INVIGORATION STATE AND METHOD OF ASSESSING | Givaudan SA (CH) | 2024-04-10 | — | — | EP | claimed |
| EP-4347760-A1 | ORAL CARE FLAVOUR FOR IMPROVING HAPPINESS STATE AND METHOD OF ASSESSING | Givaudan SA (CH) | 2024-04-10 | — | — | EP | claimed |
| CN-117396589-A | Oral care flavor and assessment method for improving pleasure status | 奇华顿股份有限公司 | 2024-01-12 | — | — | CN | claimed |
| CN-117396588-A | Oral care flavor and assessment method for improving state of agitation | 奇华顿股份有限公司 | 2024-01-12 | — | — | CN | claimed |
| EP-2265245-A2 | COOLING COSMETIC OR DERMATOLOGICAL PREPARATIONS HAVING A CONTENT OF (1R,2S,5R)-2-ISOPROPYL-5-METHYL-N-(2-(PYRIDYNE-2-YL)ETHYL-CYCLOHEXANE CARBOXAMIDE AND/OR (1R,2S,5R)-N-(4-(CYANOMETHYL)PHENYL)-2-ISPROPYL-5-METHYLCYCLOHEXANE CARBOXAMIDE FOR THE REDUCTION OF ERYTHEMA | Beiersdorf AG (DE) | 2010-12-29 | — | — | EP | claimed |
| EP-2265243-A2 | COOLING COSMETIC OR DERMATOLOGICAL PREPARATIONS HAVING A CONTENT OF (1R,2S,5R)-2-ISOPROPYL-5-METHYL-N-(2-(PYRIDYNE-2-YL)ETHYL-CYCLOHEXANE CARBOXAMIDE AND/OR (1R,2S,5R)-N-(4-(CYANOMETHYL)PHENYL)-2-ISOPROPYL-5- METHYLCYCLOHEXANE CARBOXAMIDE COMPRISING MENTHOXYPROPANE DIOL | Beiersdorf AG (DE) | 2010-12-29 | — | — | EP | claimed |
| EP-2265246-A1 | PREPARATIONS FOR REDUCING ITCHING AND OTHER PARAESTHESIAS WHICH WITH (1R,2S,5R)-2-ISOPROPYL-5-METHYL-N-(2-(PYRIDIN-2YL)ETHYLCYCLOHEXYL CARBOXAMIDE AND/OR (1R,2S,5R)-N84-(CYANOMETHYL)-PHENYL)-2-ISOPROPYL-5-METHYLCYCLOHEXYL CARBOXAMIDE | Beiersdorf AG (DE) | 2010-12-29 | — | — | EP | claimed |
| US-20100040563-A1 | Solubilization of Cyclohexane-Based Carboxamide Derivatives for Use as Sensates in Consumer Products | THE PROCTER & GAMBLE COMPANY | 2010-02-18 | — | — | US | claimed |
| US-20090311206-A1 | COOLING COSMETIC OR DERMATOLOGICAL PREPARATIONS COMPRISING (1R,2S,5R)-2-ISOPROPYL-5-METHYL-N-(2-(PYRIDIN-2-YL)ETHYL)-CYCLOHEXANE CARBOXAMIDE AND/OR (1R,2S,5R)-N-(4-CYANOMETHYL-PHENYL)-2-ISOPROPYL-5-METHYLCYCLOHEXANE CARBOXAMIDE FOR REDUCING SKIN REDDENING | BEIERSDORF AG (DE) | 2009-12-17 | — | — | US | claimed |
| US-20090306152-A1 | COOLING COSMETIC OR DERMATOLOGICAL PREPARATIONS COMPRISING (1R,2S,5R)-2-ISOPROPYL-5-METHYL-N-(2-(PYRIDIN-2-YL)ETHYL)-CYCLOHEXANE CARBOXAMIDE AND/OR (1R,2S,5R)-N-(4-CYANOMETHYL-PHENYL)-2-ISOPROPYL-5-METHYLCYCLOHEXANE CARBOXAMIDE IN COMBINATION WITH MENTHOXYPROPANEDIOL | BEIERSDORF AG. (DE) | 2009-12-10 | — | — | US | claimed |
| WO-2009127282-A1 | PREPARATIONS FOR REDUCING ITCHING AND OTHER PARAESTHESIAS WHICH WITH (1R,2S,5R)-2-ISOPROPYL-5-METHYL-N-(2-(PYRIDIN-2YL)ETHYLCYCLOHEXYL CARBOXAMIDE AND/OR (1R,2S,5R)-N84-(CYANOMETHYL)-PHENYL)-2-ISOPROPYL-5-METHYLCYCLOHEXYL CARBOXAMIDE | BEIERSDORF AG (DE) | 2009-10-22 | — | — | WO | claimed |
| WO-2009115163-A2 | COOLING COSMETIC OR DERMATOLOGICAL PREPARATIONS HAVING A CONTENT OF (1R,2S,5R)-2-ISOPROPYL-5-METHYL-N-(2-(PYRIDYNE-2-YL)ETHYL-CYCLOHEXANE CARBOXAMIDE AND/OR (1R,2S,5R)-N-(4-(CYANOMETHYL)PHENYL)-2-ISPROPYL-5-METHYLCYCLOHEXANE CARBOXAMIDE FOR THE REDUCTION OF ERYTHEMA | BEIERSDORF AG (DE) | 2009-09-24 | — | — | WO | claimed |
| WO-2009115164-A2 | COOLING COSMETIC OR DERMATOLOGICAL PREPARATIONS HAVING A CONTENT OF (1R,2S,5R)-2-ISOPROPYL-5-METHYL-N-(2-(PYRIDYNE-2-YL)ETHYL-CYCLOHEXANE CARBOXAMIDE AND/OR (1R,2S,5R)-N-(4-(CYANOMETHYL)PHENYL)-2-ISOPROPYL-5- METHYLCYCLOHEXANE CARBOXAMIDE COMPRISING MENTHOXYPROPANE DIOL | BEIERSDORF AG (DE) | 2009-09-24 | — | — | WO | claimed |
| WO-2009115165-A2 | COOLING PREPARATIONS FOR CONTACT WITH HUMAN SKIN AND/OR MUCOUS MEMBRANES, CONTAINING (1R,2S,5R)-2-ISOPROPYL-5-METHYL-N-(2-(PYRIDIN-2-YL)ETHYL-CYCLOHEXANE CARBOXAMIDE AND/OR (1R,2S,5R)-N-(4-(CYANOMETHYL)-PHENYL)-2-ISOPROPYL-5-METHYLCYCLOHEXANE CARBOXAMIDE | BEIERSDORF AG (DE) | 2009-09-24 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12600751-B2 | Modified S2 subunit of the coronavirus spike protein | SARS1, FABP2, UBE2V1 | TRPM8 4278/4885EPHX1 3673/4885KMT2A 3720/4885 |
| US-20100040563-A1 | Solubilization of Cyclohexane-Based Carboxamide Derivatives for Use as Sensates in Consumer Products | CUTA, TAS2R8, TAS2R38 | TRPM8 76/4885EPHX1 3890/4885KMT2A 3554/4885 |
| US-20090306152-A1 | COOLING COSMETIC OR DERMATOLOGICAL PREPARATIONS COMPRISING (1R,2S,5R)-2-ISOPROPYL-5-METHYL-N-(2-(PYRIDIN-2-YL)ETHYL)-CYCLOHEXANE CARBOXAMIDE AND/OR (1R,2S,5R)-N-(4-CYANOMETHYL-PHENYL)-2-ISOPROPYL-5-METHYLCYCLOHEXANE CARBOXAMIDE IN COMBINATION WITH MENTHOXYPROPANEDIOL | CUTA, ACMSD, DECR2 | TRPM8 41/4885EPHX1 889/4885KMT2A 178/4885 |
| US-20090311206-A1 | COOLING COSMETIC OR DERMATOLOGICAL PREPARATIONS COMPRISING (1R,2S,5R)-2-ISOPROPYL-5-METHYL-N-(2-(PYRIDIN-2-YL)ETHYL)-CYCLOHEXANE CARBOXAMIDE AND/OR (1R,2S,5R)-N-(4-CYANOMETHYL-PHENYL)-2-ISOPROPYL-5-METHYLCYCLOHEXANE CARBOXAMIDE FOR REDUCING SKIN REDDENING | CUTA, MC5R, MC1R | TRPM8 138/4885EPHX1 1843/4885KMT2A 119/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.