Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.65 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.39 |
| ▸ | UBE2M | P61081 | 1/20 | 0.39 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31438756 | 1.00 | TRPM8 (0.65) | TRPM8EPHX1KMT2ASERPINE1MEN1 | |
| SCHEMBL16551709 | 1.00 | TRPM8 (0.65) | TRPM8EPHX1KMT2ASERPINE1MEN1 | |
| SCHEMBL4127806 | 1.00 | TRPM8 (0.65) | TRPM8EPHX1KMT2ASERPINE1MEN1 | |
| SCHEMBL16004827 | 1.00 | TRPM8 (0.65) | TRPM8EPHX1KMT2ASERPINE1MEN1 | |
| SCHEMBL3219019 | 1.00 | TRPM8 (0.65) | TRPM8EPHX1KMT2ASERPINE1MEN1 | |
| SCHEMBL584077 | 1.00 | TRPM8 (0.65) | TRPM8EPHX1KMT2ASERPINE1MEN1 | |
| SCHEMBL10044268 | 1.00 | TRPM8 (0.65) | TRPM8EPHX1KMT2ASERPINE1MEN1 | |
| SCHEMBL16551708 | 1.00 | TRPM8 (0.65) | TRPM8EPHX1KMT2ASERPINE1MEN1 | |
| SCHEMBL18812290 | 0.89 | TRPM8 (0.62) | TRPM8EPHX1KMT2ASERPINE1MEN1 | |
| SCHEMBL2628763 | 0.86 | TRPM8 (0.70) | TRPM8EPHX1KMT2ASERPINE1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1644 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122028893-A | Composition and method for producing the same | 奇华顿股份有限公司 | 2026-05-12 | — | — | CN | claimed |
| EP-3817575-B1 | SOLUBILISATION OF COOLING AGENTS OF LOW SOLUBILITY | SYMRISE AG (DE) | 2025-10-15 | — | — | EP | claimed |
| US-12414906-B2 | Compositions and methods for treating hot flashes | THE PROCTER & GAMBLE COMPANY (US) | 2025-09-16 | — | — | US | claimed |
| US-20250163006-A1 | New Coolants, and Preparations Containing Same | SYMRISE AG (DE) | 2025-05-22 | — | — | US | claimed |
| WO-2025078256-A1 | COMPOSITION | GIVAUDAN SA (CH) | 2025-04-17 | — | — | WO | claimed |
| US-20250066320-A1 | Active Ingredients with Sialagogue and Tingling/Fizzy Effect, and Preparations Containing Same | SYMRISE AG (DE) | 2025-02-27 | — | — | US | claimed |
| WO-2025026525-A1 | HETEROCYCLIC COMPOUNDS AS PHYSIOLOGICAL COOLANTS | SYMRISE AG (DE) | 2025-02-06 | — | — | WO | claimed |
| EP-4469439-A1 | NEW COOLANTS, AND PREPARATIONS CONTAINING SAME | Symrise AG (DE) | 2024-12-04 | — | — | EP | claimed |
| EP-4452941-A1 | ACTIVE INGREDIENTS WITH SIALAGOGUE AND TINGLING/FIZZY EFFECT, AND PREPARATIONS CONTAINING SAME | Symrise AG (DE) | 2024-10-30 | — | — | EP | claimed |
| CN-118829416-A | Composition (III) | 西姆莱斯股份公司 | 2024-10-22 | — | — | CN | claimed |
| EP-2168957-A2 | Alkyl-substituted tetrahydropyranes as aromatic materials | Symrise GmbH & Co. KG (DE) | 2010-03-31 | — | — | EP | claimed |
| EP-2162018-A1 | SALT ENHANCEMENT | Givaudan SA (CH) | 2010-03-17 | — | — | EP | claimed |
| WO-2009140783-A1 | COOLING COMPOSITION | GIVAUDAN SA (CH) | 2009-11-26 | — | — | WO | claimed |
| US-20090240223-A1 | ABSORBENT ARTICLE COMPRISING LOTION COMPOSITION COMPRISING A COOLING AGENT | PROCTER & GAMBLE COMPANY, THE | 2009-09-24 | — | — | US | claimed |
| WO-2009105740-A2 | ABSORBENT ARTICLE COMPRISING LOTION COMPOSITION COMPRISING A COOLING AGENT | THE PROCTER & GAMBLE COMPANY (US) | 2009-08-27 | — | — | WO | claimed |
| US-20080311266-A1 | Salt Enhancement | GRAY KIMBERLEY H | 2008-12-18 | — | — | US | claimed |
| WO-2008148234-A1 | SALT ENHANCEMENT | GIVAUDAN SA (CH) | 2008-12-11 | — | — | WO | claimed |
| WO-2008138162-A1 | COMPOSITIONS AND THEIR USE | GIVAUDAN SA (CH) | 2008-11-20 | — | — | WO | claimed |
| US-7414152-B2 | e. g. N-(4-cyanomethylphenyl) p-menthanecarboxamide; cooling agent in cosmetics and food industries; with additional cooling compound such as menthol, menthone, isopulegol | GIVAUDAN, SA (CH) | 2008-08-19 | — | — | US | claimed |
| US-20060276667-A1 | N-substituted p-menthane carboxamides | GIVAUDAN-SA | 2006-12-07 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060276667-A1 | N-substituted p-menthane carboxamides | ME2, ME3, PYM1 | TRPM8 45/4885EPHX1 268/4885KMT2A 906/4885 |
| US-20250066320-A1 | Active Ingredients with Sialagogue and Tingling/Fizzy Effect, and Preparations Containing Same | TAS2R5, TAS2R7, TAS2R8 | TRPM8 363/4885EPHX1 2617/4885KMT2A 2748/4885 |
| US-12414906-B2 | Compositions and methods for treating hot flashes | ELOVL5, ELOVL3, HCN3 | TRPM8 672/4885EPHX1 1620/4885KMT2A 4355/4885 |
| US-20250163006-A1 | New Coolants, and Preparations Containing Same | TTR, TAS2R5, TAS2R50 | TRPM8 152/4885EPHX1 2081/4885KMT2A 3992/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.