Known targets — ChEMBL curated mechanism
CHRM1CHRM2CHRM3CHRM4CHRM5SLC6A2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | THPO | P40225 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 3/20 | 0.35 |
| ▸ | CA9 | Q16790 | 3/20 | 0.35 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5849458 | 0.92 | MAPT (0.37) | TDP1MAPK1MAPTMEN1KMT2A | |
| SCHEMBL5849477 | 0.84 | L3MBTL1 (0.35) | TDP1L3MBTL1MAPK1MAPTCA12 | |
| SCHEMBL1001338 | 0.83 | MMP13 (0.42) | TDP1L3MBTL1CYP3A4CYP2D6MAPK1 | |
| Trifluoromethanesulfonic Acid SCHEMBL5850147 | 0.81 | PTGS1 (0.39) | TDP1L3MBTL1MAPK1MAPTALDH1A1 | |
| SCHEMBL298034 | 0.81 | SIRT1 (0.40) | TDP1L3MBTL1MAPK1LMNAMAPT | |
| SCHEMBL2634898 | 0.80 | KCNH2 (0.43) | CYP2D6LMNACA12CA9CA1 | |
| SCHEMBL3127290 | 0.80 | CA12 (0.40) | TDP1L3MBTL1CYP3A4CYP2D6MAPK1 | |
| SCHEMBL7133269 | 0.79 | CA12 (0.47) | TDP1L3MBTL1CYP3A4CYP2D6MAPK1 | |
| Hydrochloric Acid SCHEMBL8980364 | 0.79 | SIRT1 (0.39) | TDP1L3MBTL1MAPK1LMNAMAPT | |
| SCHEMBL64189 | 0.79 | CA12 (0.47) | TDP1L3MBTL1CYP3A4CYP2D6MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6984473-B2 | Light blocking; amplified photoresist; acid generators; high density semiconductors | MITSUBISHI DENKI KABUSHIKI KAISHA (JP) | 2006-01-10 | — | — | US | disclosed |
| US-20030152845-A1 | Mask blank, protective film therefor and method of patterning mask blank | MITSUBISHI DENKI KABUSHIKI KAISHA (JP) | 2003-08-14 | — | — | US | disclosed |