Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of P-Cresol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| P-Cresol SCHEMBL8157029 | 0.93 | ACHE (0.57) | — | |
| P-Cresol SCHEMBL8423863 | 0.93 | ACHE (0.57) | — | |
| P-Cresol SCHEMBL1229546 | 0.93 | ACHE (0.57) | — | |
| P-Cresol SCHEMBL10728842 | 0.93 | ACHE (0.57) | — | |
| P-Cresol SCHEMBL585475 | 0.93 | — | — | |
| P-Cresol SCHEMBL1228560 | 0.93 | ACHE (0.57) | — | |
| P-Cresol SCHEMBL585229 | 0.93 | — | — | |
| P-Cresol SCHEMBL1229426 | 0.93 | ACHE (0.57) | — | |
| P-Cresol SCHEMBL6063969 | 0.93 | ACHE (0.57) | — | |
| P-Cresol SCHEMBL6039896 | 0.90 | ACHE (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 135 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114950547-A | Preparation method of sodium phenolate modified hydrotalcite and application of hydrotalcite in preparation of phenol ether perfume | 常州大学 | 2022-08-30 | — | — | CN | claimed |
| CN-112251183-B | Pressure-sensitive hot melt adhesive capable of being used at low temperature and preparation method thereof | 广东互典缓冲材料技术有限公司 | 2022-04-12 | — | — | CN | claimed |
| CN-112266461-B | Buffer material capable of being used in low-temperature environment and preparation method and application thereof | 广东互典缓冲材料技术有限公司 | 2022-04-12 | — | — | CN | claimed |
| CN-113998824-A | Production method and equipment for reducing salt content and solid waste of p-methylphenol | 金能科技股份有限公司 | 2022-02-01 | — | — | CN | claimed |
| CN-112266461-A | Buffer material capable of being used in low-temperature environment and preparation method and application thereof | 广东互典缓冲材料技术有限公司 | 2021-01-26 | — | — | CN | claimed |
| CN-112251183-A | Pressure-sensitive hot melt adhesive capable of being used at low temperature and preparation method thereof | 广东互典缓冲材料技术有限公司 | 2021-01-22 | — | — | CN | claimed |
| CN-107628931-B | Micro-reaction system and method for synthesizing anisole and derivatives thereof | 清华大学 | 2020-05-29 | — | — | CN | claimed |
| CN-109503663-A | A kind of industrialized preparing process of bis- (2,6- di-t-butyl -4- aminomethyl phenyl) pentaerythritol phosphites | 萧县新秀新材料有限公司 | 2019-03-22 | — | — | CN | claimed |
| US-20160340460-A1 | SULFONATED POLYPHOSPHAZENE COPOLYMER PROTON EXCHANGE MEMBRANE MATERIAL AND METHOD FOR PREPARING SUCH MEMBRANE | XU, Hulin (CN) | 2016-11-24 | — | — | US | claimed |
| US-20040225153-A1 | Synthesis of polyphosphazenes with sulfonimide side groups | THE PENN STATE RESEARCH FOUNDATION | 2004-11-11 | — | — | US | claimed |
| WO-2004072141-A2 | SYNTHESIS OF POLYPHOSPHAZENES WITH SULFONIMIDE SIDE GROUPS | THE PENN STATE RESEARCH FOUNDATION (US) | 2004-08-26 | — | — | WO | claimed |
| EP-0291542-B1 | HYDRAULIC FLUID | ETHYL CORPORATION (US) | 1991-01-02 | — | — | EP | claimed |
| EP-0291542-A1 | Hydraulic fluid | ETHYL CORPORATION (US) | 1988-11-23 | — | — | EP | claimed |
| US-4698439-A | HYDRAULIC FLUIDS | ETHYL CORPORATION (US) | 1987-10-06 | — | — | US | claimed |
| CN-114950547-A | Preparation method of sodium phenolate modified hydrotalcite and application of hydrotalcite in preparation of phenol ether perfume | 常州大学 | 2022-08-30 | — | — | CN | disclosed |
| CN-114804493-A | Device and method for extracting cresol as byproduct in production process of methyl fluorobenzene | 东至德泰精细化工有限公司 | 2022-07-29 | — | — | CN | disclosed |
| CN-112251183-B | Pressure-sensitive hot melt adhesive capable of being used at low temperature and preparation method thereof | 广东互典缓冲材料技术有限公司 | 2022-04-12 | — | — | CN | disclosed |
| US-4053456-A | CROSSLINKING, SMOKELESS | ARMSTRONG CORK COMPANY (US) | 1977-10-11 | — | — | US | disclosed |
| US-4026838-A | INCORPORATING A SOLID CARBOXYLIC ACID | ARMSTRONG CORK COMPANY (US) | 1977-05-31 | — | — | US | disclosed |
| US-3975415-A | DIMERIZATION CATALYSTS FOR BUTADIENE | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1976-08-17 | — | — | US | disclosed |