Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100A4 | P26447 | 2/20 | 0.46 |
| ▸ | GPR35 | Q9HC97 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20985115 | 0.97 | S100A4 (0.48) | S100A4GPR35MEN1KMT2ALMNA | |
| SCHEMBL1502113 | 0.97 | S100A4 (0.48) | S100A4GPR35MEN1KMT2ALMNA | |
| Water SCHEMBL3516244 | 0.93 | S100A4 (0.46) | S100A4GPR35MEN1KMT2ALMNA | |
| SCHEMBL28726007 | 0.93 | S100A4 (0.46) | S100A4GPR35MEN1KMT2ALMNA | |
| SCHEMBL31123045 | 0.93 | S100A4 (0.46) | S100A4GPR35MEN1KMT2ALMNA | |
| SCHEMBL28666838 | 0.93 | S100A4 (0.46) | S100A4GPR35MEN1KMT2ALMNA | |
| SCHEMBL5860030 | 0.93 | S100A4 (0.46) | S100A4GPR35MEN1KMT2ALMNA | |
| Methyl Alcohol SCHEMBL29086936 | 0.90 | S100A4 (0.44) | S100A4GPR35MEN1KMT2ALMNA | |
| SCHEMBL70525 | 0.90 | S100A4 (0.44) | S100A4GPR35MEN1KMT2ALMNA | |
| SCHEMBL3083248 | 0.90 | S100A4 (0.48) | S100A4GPR35MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11814332-B2 | Bismuth-based energetic materials | SELLIER & BELLOT A.S. (CZ) | 2023-11-14 | — | — | US | disclosed |
| EP-3066054-B1 | BISMUTH-BASED ENERGETIC MATERIALS | SELLIER & BELLOT AS (CZ) | 2021-03-24 | — | — | EP | disclosed |
| US-20190152873-A1 | BISMUTH-BASED ENERGETIC MATERIALS | SELLIER & BELLOT A.S. (CZ) | 2019-05-23 | — | — | US | disclosed |
| US-20160280614-A1 | BISMUTH-BASED ENERGETIC MATERIALS | SELLIER & BELLOT A.S. (CZ) | 2016-09-29 | — | — | US | disclosed |
| EP-3066054-A1 | BISMUTH-BASED ENERGETIC MATERIALS | Sellier & Bellot A.S. (CZ) | 2016-09-14 | — | — | EP | disclosed |
| WO-2015067228-A1 | BISMUTH-BASED ENERGETIC MATERIALS | SELLIER & BELLOT A.S. (CZ) | 2015-05-14 | — | — | WO | disclosed |
| US-7057073-B2 | Synthesis of trinitrophloroglucinol and triaminotrinitrobenzene (TATB) | REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2006-06-06 | — | — | US | disclosed |
| US-20050070743-A1 | Synthesis of trinitrophloroglucinol and triaminotrinitrobenzene (TATB) | LAWRENCE LIVERMORE NATIONAL SECURITY, LLC | 2005-03-31 | — | — | US | disclosed |