Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CASP1 | P29466 | 2/20 | 0.38 |
| ▸ | CASP7 | P55210 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5754107 | 0.91 | ALDH1A1 (0.41) | ALDH1A1HPGDKDM4ECYP3A4CYP2C19 | |
| SCHEMBL5864191 | 0.91 | PDE4A (0.39) | ALDH1A1HPGDKDM4EMAPT | |
| SCHEMBL5864327 | 0.90 | CYP2C19 (0.40) | ALDH1A1NPSR1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL5863779 | 0.89 | TDP1 (0.36) | CYP3A4CYP2C19MAPTTP53MAPK8 | |
| SCHEMBL4524816 | 0.88 | EGFR (0.43) | ALDH1A1HPGDKDM4ENPSR1CYP3A4 | |
| SCHEMBL5786959 | 0.86 | L3MBTL1 (0.37) | ALDH1A1HPGDKDM4ECYP3A4CYP2C19 | |
| SCHEMBL5752888 | 0.86 | KIF11 (0.41) | HPGDKDM4EUSP2CYP1A2CYP3A4 | |
| SCHEMBL5863739 | 0.86 | MAPK8 (0.38) | ALDH1A1KDM4EUSP2CYP1A2CYP3A4 | |
| SCHEMBL5754034 | 0.84 | GRIN1 (0.39) | KDM4ECYP1A2CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL5864291 | 0.83 | TDP1 (0.42) | ALDH1A1HPGDKDM4ENPSR1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7041676-B2 | Compounds, compositions, and methods | CYTOKINETICS, INC. (US) | 2006-05-09 | — | — | US | disclosed |
| US-20060019988-A1 | Compounds for treating cell prolifieration disease with of kinesin activity , anticancer activity | CYTOKINETICS, INC. | 2006-01-26 | — | — | US | disclosed |
| US-20040082567-A1 | Compounds, compositions, and methods | CYTOKINETICS, INC. | 2004-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060019988-A1 | Compounds for treating cell prolifieration disease with of kinesin activity , anticancer activity | KIF5B, KIF2C, KIF18A | ALDH1A1 1833/4885HPGD 1691/4885KDM4E 1744/4885 |
| US-20040082567-A1 | Compounds, compositions, and methods | ALPP, PCNA, MKI67 | ALDH1A1 2274/4885HPGD 802/4885KDM4E 1780/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.