SCHEMBL58731

SCHEMBL58731

O=Pc1cccc(C(=O)c2c(Cl)cccc2Cl)c1C(=O)c1c(Cl)cccc1Cl

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.42
PBRM1 Q86U86 1/20 0.41
TSHR P16473 1/20 0.39
CES2 O00748 1/20 0.38
CES1 P23141 1/20 0.38
GABRP O00591 2/20 0.37
GABRD O14764 2/20 0.37
GABRA1 P14867 2/20 0.37
GABRB1 P18505 2/20 0.37
GABRG2 P18507 2/20 0.37
GABRB3 P28472 2/20 0.37
GABRA5 P31644 2/20 0.37
GABRA3 P34903 2/20 0.37
GABRA2 P47869 2/20 0.37
GABRB2 P47870 2/20 0.37
GABRA4 P48169 2/20 0.37
GABRE P78334 2/20 0.37
GABRA6 Q16445 2/20 0.37
GABRG1 Q8N1C3 2/20 0.37
GABRG3 Q99928 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10322311 0.88 PBRM1 (0.45) ALDH1A1PBRM1TSHRCES2CES1
SCHEMBL1594842 0.82 ALDH1A1 (0.45) ALDH1A1PBRM1TSHRGABRPGABRD
SCHEMBL3189829 0.79 HSD17B10 (0.38) ALDH1A1TSHRKDM4ELMNACYP1A2
SCHEMBL986817 0.77 LMNA (0.36) ALDH1A1TSHRKDM4ELMNACYP1A2
SCHEMBL9726458 0.77 ALDH1A1 (0.67) ALDH1A1PBRM1TSHRCES2CES1
SCHEMBL346600 0.76 CA12 (0.47) TSHRGAA
SCHEMBL345382 0.75 AKR1C3 (0.52) ALDH1A1CYP2C9POLBGAA
SCHEMBL9515912 0.75 ALDH1A1 (0.45) ALDH1A1PBRM1TSHRCES2CES1
Hydrogen Sulfide SCHEMBL28875010 0.74 KMT2A (0.37) ALDH1A1KDM4ELMNACYP3A4CYP2C9
SCHEMBL1595642 0.73 ALDH1A1 (0.39) ALDH1A1GABRPGABRDGABRA1GABRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 970 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250051500-A1 RADIATION-CURABLE COMPOSITION MARABU GMBH & CO. KG (DE) 2025-02-13 US claimed
US-12024136-B2 Ultra-fast curing scratch-resistant headlight restoration coating ILLINOIS TOOL WORKS INC. (US) 2024-07-02 US claimed
EP-4056658-A1 RADIATION-CURABLE COMPOUND Marabu GmbH & Co. KG (DE) 2022-09-14 EP claimed
EP-0184095-B1 BISACYLPHOSPHINOXIDES, THEIR PREPARATION AND USE ESPE Stiftung & Co Produktions- und Vertriebs KG (DE) 1989-07-05 EP claimed
US-4737593-A PHOTOINITIATORS FOR ADDITION POLYMERIZATION; DENTISTRY Fabrik Pharmazeutischer Praparate (DE) 1988-04-12 US claimed
US-12622847-B2 Organosilicon compound and dental composition containing same KURARAY NORITAKE DENTAL INC. (JP) 2026-05-12 US disclosed
EP-3861977-B1 (METH)ACRYLATE, MONOMER COMPOSITION, MOLDED BODY, COMPOSITION FOR DENTAL MATERIAL, AND DENTAL MATERIAL MITSUI CHEMICALS INC (JP) 2026-05-06 EP disclosed
US-12617887-B2 Resin composition for stereolithography KURARAY NORITAKE DENTAL INC. (JP) 2026-05-05 US disclosed
EP-3862373-B1 RESIN COMPOSITION FOR OPTICAL SHAPING KURARAY NORITAKE DENTAL INC (JP) 2026-04-22 EP disclosed
US-12605306-B2 Method of manufacturing monomer composition, raw material composition, monomer composition, curable composition, and molded body MITSUI CHEMICALS, INC. (JP) 2026-04-21 US disclosed
EP-3419051-B1 CURABLE RESIN COMPOSITION AND FAN OUT TYPE WAFER LEVEL PACKAGE TAIYO HOLDINGS CO LTD (JP) 2026-04-08 EP disclosed
EP-4722266-A1 STEREOLITHOGRAPHIC RESIN COMPOSITION Kuraray Noritake Dental Inc. (JP) 2026-04-08 EP disclosed
EP-1069163-A1 Photocurable coating composition for road markings SHOWA DENKO KABUSHIKI KAISHA (JP) 2001-01-17 EP disclosed
EP-1048707-A1 PHOTOCURABLE ADHESIVE COMPOSITION, RESIN LAMINATE MADE BY USING THE SAME, AND PROCESS FOR PRODUCING THE SAME Showa Denko Kabushiki Kaisha (JP) 2000-11-02 EP disclosed
WO-2000032612-A1 PROCESS FOR PREPARING ACYLPHOSPHINES AND DERIVATIVES CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2000-06-08 WO disclosed
EP-1002817-A2 Photocurable composition SHOWA DENKO KABUSHIKI KAISHA (JP) 2000-05-24 EP disclosed
JP-2000016910-A PHOTOCURABLE DENTAL MATERIAL TOKUYAMA CORP 2000-01-18 JP disclosed
EP-0915136-A1 Photocurable paint composition for road markings SHOWA DENKO KABUSHIKI KAISHA (JP) 1999-05-12 EP disclosed
US-4792632-A ADDITION POLYMER PHOTOINITIATORS ESPE FABRIK PHARMAZEUTISCHER PRAPARATE GMBH (DE) 1988-12-20 US disclosed
US-4737593-A PHOTOINITIATORS FOR ADDITION POLYMERIZATION; DENTISTRY Fabrik Pharmazeutischer Praparate (DE) 1988-04-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12605306-B2 Method of manufacturing monomer composition, raw material composition, monomer composition, curable composition, and molded body ADH1A, ADH1C, ADH5 ALDH1A1 15/4885PBRM1 1710/4885TSHR 3001/4885
US-12622847-B2 Organosilicon compound and dental composition containing same MSL1, ITGA1, ITGAL ALDH1A1 668/4885PBRM1 1763/4885TSHR 4185/4885
US-12617887-B2 Resin composition for stereolithography MAT2B, MAT1A, ARCN1 ALDH1A1 339/4885PBRM1 3093/4885TSHR 4345/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.