SCHEMBL5873354

SCHEMBL5873354

O=C(O)c1ccc([Se][Se]c2ccc(C(=O)O)cc2)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.67
TP53 P04637 1/20 0.67
SRD5A2 P31213 5/20 0.57
CA1 P00915 3/20 0.55
CA2 P00918 3/20 0.55
CA12 O43570 1/20 0.55
CA3 P07451 1/20 0.55
TYR P14679 1/20 0.55
DRD1 P21728 1/20 0.55
CA4 P22748 1/20 0.55
CA6 P23280 1/20 0.55
CA5A P35218 1/20 0.55
CA7 P43166 1/20 0.55
CA9 Q16790 1/20 0.55
CA14 Q9ULX7 1/20 0.55
CA5B Q9Y2D0 1/20 0.55
DAO P14920 1/20 0.52
NAPRT Q6XQN6 1/20 0.52
ALDH1A1 P00352 2/20 0.52
ALOX15 P16050 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Terephthalic Acid SCHEMBL2511919 0.82 TSHR (1.00) TSHRTP53SRD5A2CA1CA2
Terephthalic Acid SCHEMBL5053781 0.82 TSHR (1.00) TSHRTP53SRD5A2CA1CA2
Terephthalic Acid SCHEMBL175823 0.82 TSHR (1.00) TSHRTP53SRD5A2CA1CA2
Terephthalic Acid SCHEMBL1655 0.82 TSHR (1.00) TSHRTP53SRD5A2CA1CA2
Terephthalic Acid SCHEMBL25381766 0.78 TSHR (0.92) TSHRTP53SRD5A2CA1CA2
Terephthalic Acid SCHEMBL3244094 0.78 TSHR (0.92) TSHRTP53SRD5A2CA1CA2
Terephthalic Acid SCHEMBL9484769 0.78 TSHR (0.92) TSHRTP53SRD5A2CA1CA2
Terephthalic Acid SCHEMBL20704876 0.78 TSHR (0.92) TSHRTP53SRD5A2CA1CA2
Terephthalic Acid SCHEMBL21443891 0.78 TSHR (0.92) TSHRTP53SRD5A2CA1CA2
Terephthalic Acid SCHEMBL108476 0.78 TSHR (0.92) TSHRTP53SRD5A2CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12285412-B1 Organoselenium benzimidazole compounds for treating cancer IMAM MOHAMMAD IBN SAUD ISLAMIC UNIVERSITY (SA) 2025-04-29 US claimed
CN-118304471-A Long-acting functionalized double-layer bionic small-caliber artificial blood vessel and preparation method and application thereof 上海工程技术大学 2024-07-09 CN claimed
US-12285412-B1 Organoselenium benzimidazole compounds for treating cancer IMAM MOHAMMAD IBN SAUD ISLAMIC UNIVERSITY (SA) 2025-04-29 US disclosed
CN-118304471-B Long-acting functionalized double-layer bionic small-caliber artificial blood vessel and preparation method and application thereof 上海工程技术大学 2024-10-29 CN disclosed
CN-118304471-A Long-acting functionalized double-layer bionic small-caliber artificial blood vessel and preparation method and application thereof 上海工程技术大学 2024-07-09 CN disclosed
US-11845750-B1 Antiproliferative selenated-folate hybrids King Faisal University (SA) 2023-12-19 US disclosed
US-7045360-B2 Method for analysis of reaction products PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2006-05-16 US disclosed
US-20020090728-A1 Method for analysis of reaction products PRESIDENT AND FELLOWS OF HARVARD COLLEGE 2002-07-11 US disclosed
WO-2001057526-A1 METHOD FOR ANALYSIS OF REACTION PRODUCTS PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2001-08-09 WO disclosed
US-4177071-A HIGH SENSITIVITY TO PENTRATING RADIATION; INSENSITIVE TO FORMATION OF PRESSURE MARKS AGFA-GEVAERT, N.V. (BE) 1979-12-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11845750-B1 Antiproliferative selenated-folate hybrids DHFR, FOLR2, MTHFD1 TSHR 1828/4885TP53 192/4885SRD5A2 465/4885
US-12285412-B1 Organoselenium benzimidazole compounds for treating cancer GPX4, ZFR, BRPF3 TSHR 2777/4885TP53 107/4885SRD5A2 1716/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.