Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2C | P18825 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | RGS12 | O14924 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25367842 | 1.00 | ADRA2C (0.50) | ADRA2CKDM4EADRA2ALMNAHIF1A | |
| SCHEMBL14145089 | 1.00 | ADRA2C (0.50) | ADRA2CKDM4EADRA2ALMNAHIF1A | |
| SCHEMBL12894107 | 0.84 | THRB (0.50) | ADRA2CKDM4EADRA2ALMNAHIF1A | |
| SCHEMBL3842608 | 0.83 | THRB (0.57) | LMNATHRBALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL5474351 | 0.83 | THRB (0.57) | LMNATHRBALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL5396533 | 0.83 | THRB (0.57) | LMNATHRBALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL5474344 | 0.83 | THRB (0.57) | LMNATHRBALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL6558895 | 0.82 | THRB (0.53) | ADRA2CKDM4EADRA2ALMNAHIF1A | |
| SCHEMBL7958881 | 0.82 | THRB (0.53) | ADRA2CKDM4EADRA2ALMNAHIF1A | |
| SCHEMBL9842268 | 0.81 | LMNA (0.48) | ADRA2CKDM4EADRA2ALMNAHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6989052-B1 | Phase change ink printing process | XEROX CORPORATION (US) | 2006-01-24 | — | — | US | claimed |
| US-20060004123-A1 | PHASE CHANGE INK PRINTING PROCESS | XEROX CORPORATION | 2006-01-05 | — | — | US | claimed |
| US-20240400517-A1 | CHIRAL BIMETALLIC COOPERATIVE CATALYSIS SYSTEM AND USE THEREOF IN ASYMMETRIC SYNTHESIS OF BEDAQUILINE | SHANGHAI JIAO TONG UNIVERSITY (CN) | 2024-12-05 | — | — | US | disclosed |
| WO-2023151700-A1 | DOUBLE-CHIRAL METAL COOPERATIVE CATALYSIS SYSTEM AND USE THEREOF IN ASYMMETRIC SYNTHESIS OF BEDAQUILINE | 上海交通大学 | 2023-08-17 | — | — | WO | disclosed |
| CN-116024281-A | Method for degrading lignin by mechanochemical enzyme coupling | 浙江工业大学 | 2023-04-28 | — | — | CN | disclosed |
| US-9359391-B2 | Selective C—O bond cleavage of oxidized lignin and lignin-type materials into simple aromatic compounds | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2016-06-07 | — | — | US | disclosed |
| US-20150259368-A1 | SELECTIVE C-O BOND CLEAVAGE OF OXIDIZED LIGNIN AND LIGNIN-TYPE MATERIALS INTO SIMPLE AROMATIC COMPOUNDS | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2015-09-17 | — | — | US | disclosed |
| WO-2015138563-A1 | SELECTIVE C-O BOND CLEAVAGE OF OXIDIZED LIGNIN AND LIGNIN-TYPE MATERIALS INTO SIMPLE AROMATIC COMPOUNDS | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2015-09-17 | — | — | WO | disclosed |
| US-8969534-B2 | Selective aerobic alcohol oxidation method for conversion of lignin into simple aromatic compounds | Wisconsin Alumni Research Foundataion (US) | 2015-03-03 | — | — | US | disclosed |
| US-20140235838-A1 | SELECTIVE AEROBIC ALCOHOL OXIDATION METHOD FOR CONVERSION OF LIGNIN INTO SIMPLE AROMATIC COMPOUNDS | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2014-08-21 | — | — | US | disclosed |
| EP-1299335-B1 | CHIRAL COMPOUNDS II | MERCK PATENT GMBH (DE) | 2007-09-05 | — | — | EP | disclosed |
| US-6989052-B1 | Phase change ink printing process | XEROX CORPORATION (US) | 2006-01-24 | — | — | US | disclosed |
| US-20060004123-A1 | PHASE CHANGE INK PRINTING PROCESS | XEROX CORPORATION | 2006-01-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240400517-A1 | CHIRAL BIMETALLIC COOPERATIVE CATALYSIS SYSTEM AND USE THEREOF IN ASYMMETRIC SYNTHESIS OF BEDAQUILINE | MAP2K4, MAP2K7, MAP2K5 | ADRA2C 505/4885KDM4E 631/4885ADRA2A 1118/4885 |
| US-20150259368-A1 | SELECTIVE C-O BOND CLEAVAGE OF OXIDIZED LIGNIN AND LIGNIN-TYPE MATERIALS INTO SIMPLE AROMATIC COMPOUNDS | AOC2, AOX1, AOC3 | ADRA2C 1674/4885KDM4E 184/4885ADRA2A 3833/4885 |
| US-20140235838-A1 | SELECTIVE AEROBIC ALCOHOL OXIDATION METHOD FOR CONVERSION OF LIGNIN INTO SIMPLE AROMATIC COMPOUNDS | AOX1, SOD1, NOX4 | ADRA2C 910/4885KDM4E 715/4885ADRA2A 997/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.