Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.34 |
| ▸ | PLAU | P00749 | 2/20 | 0.34 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | LDHB | P07195 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | AGER | Q15109 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17628560 | 0.85 | PLAU (0.44) | ALDH1A1MAPTSMN1; SMN2TDP1PLAU | |
| SCHEMBL12314678 | 0.76 | PLAU (0.33) | ALDH1A1MAPTSMN1; SMN2PLAUHCAR2 | |
| SCHEMBL9319709 | 0.75 | ALDH1A1 (0.42) | ALDH1A1MAPTSMN1; SMN2TDP1KDM4E | |
| SCHEMBL14891402 | 0.75 | PLAU (0.58) | ALDH1A1MAPTSMN1; SMN2TDP1PLAU | |
| SCHEMBL275483 | 0.73 | ATR (0.44) | ALDH1A1MAPTSMN1; SMN2TDP1KDM4E | |
| SCHEMBL30588535 | 0.73 | ATR (0.44) | ALDH1A1MAPTSMN1; SMN2TDP1KDM4E | |
| SCHEMBL22382 | 0.72 | ALDH1A1 (0.55) | ALDH1A1MAPTSMN1; SMN2TDP1LDHA | |
| SCHEMBL20540894 | 0.71 | TTR (0.39) | ALDH1A1MAPTSMN1; SMN2TDP1KDM4E | |
| SCHEMBL25285259 | 0.70 | RXFP1 (0.31) | — | |
| SCHEMBL2343868 | 0.70 | TDP1 (0.37) | TDP1PLAUKDM4EHCAR2COPS5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3700578-B1 | SYSTEMS FOR RENAL FUNCTION DETERMINATION | MEDIBEACON INC (US) | 2025-12-03 | — | — | EP | disclosed |
| US-12303570-B2 | Compositions and methods for assessing eye vasculature | MEDIBEACON INC. (US) | 2025-05-20 | — | — | US | disclosed |
| US-20230173111-A1 | COMPOSITIONS AND SYSTEMS FOR RENAL FUNCTION DETERMINATION | MEDIBEACON INC. | 2023-06-08 | — | — | US | disclosed |
| US-20230173111-A1 | COMPOSITIONS AND SYSTEMS FOR RENAL FUNCTION DETERMINATION | MEDIBEACON INC. | 2023-06-08 | — | — | US | disclosed |
| US-20230173111-A1 | COMPOSITIONS AND SYSTEMS FOR RENAL FUNCTION DETERMINATION | MEDIBEACON INC. | 2023-06-08 | — | — | US | disclosed |
| US-20230158175-A1 | METHODS FOR RENAL FUNCTION DETERMINATION | MEDIBEACON INC. | 2023-05-25 | — | — | US | disclosed |
| US-20230158175-A1 | METHODS FOR RENAL FUNCTION DETERMINATION | MEDIBEACON INC. | 2023-05-25 | — | — | US | disclosed |
| US-20230158175-A1 | METHODS FOR RENAL FUNCTION DETERMINATION | MEDIBEACON INC. | 2023-05-25 | — | — | US | disclosed |
| US-20230132384-A9 | COMPOSITIONS AND METHODS FOR ASSESSING EYE VASCULATURE | MEDIBEACON INC. | 2023-04-27 | — | — | US | disclosed |
| US-20230132384-A9 | COMPOSITIONS AND METHODS FOR ASSESSING EYE VASCULATURE | MEDIBEACON INC. | 2023-04-27 | — | — | US | disclosed |
| US-8115000-B2 | Pyrazine derivatives and uses thereof in renal monitoring | MALLINCKRODT LLC (US) | 2012-02-14 | — | — | US | disclosed |
| US-20100233091-A1 | Pyrazine Derivatives with Extended Conjugation and Methods of Using the same in Optical Applications | MEDIBEACON, INC. | 2010-09-16 | — | — | US | disclosed |
| US-20090198053-A1 | Pyrazine Derivatives and Uses Thereof in Renal Monitoring | MEDIBEACON INC. | 2009-08-06 | — | — | US | disclosed |
| US-20090198053-A1 | Pyrazine Derivatives and Uses Thereof in Renal Monitoring | MEDIBEACON INC. | 2009-08-06 | — | — | US | disclosed |
| US-20090198053-A1 | Pyrazine Derivatives and Uses Thereof in Renal Monitoring | MEDIBEACON INC. | 2009-08-06 | — | — | US | disclosed |
| EP-2038261-A2 | PYRAZINE DERIVATIVES WITH EXTENDED CONJUGATION AND USES THEREOF | Mallinckrodt Inc. (US) | 2009-03-25 | — | — | EP | disclosed |
| EP-2029554-A1 | PYRAZINE DERIVATIVES AND USES THEREOF IN RENAL MONITORING | Mallinckrodt, Inc. (US) | 2009-03-04 | — | — | EP | disclosed |
| WO-2007149478-A2 | PYRAZINE DERIVATIVES WITH EXTENDED CONJUGATION AND USES THEREOF | MALLINCKRODT INC. (US) | 2007-12-27 | — | — | WO | disclosed |
| WO-2007149479-A1 | PYRAZINE DERIVATIVES AND USES THEREOF IN RENAL MONITORING | MALLINCKRODT INC. (US) | 2007-12-27 | — | — | WO | disclosed |
| WO-2007149479-A1 | PYRAZINE DERIVATIVES AND USES THEREOF IN RENAL MONITORING | MALLINCKRODT INC. (US) | 2007-12-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230132384-A9 | COMPOSITIONS AND METHODS FOR ASSESSING EYE VASCULATURE | LIPG, FLT4, FABP3 | ALDH1A1 1933/4885MAPT 2840/4885SMN1; SMN2 4165/4885 |
| US-20230173111-A1 | COMPOSITIONS AND SYSTEMS FOR RENAL FUNCTION DETERMINATION | GLS, ATP6V1B1, REN | ALDH1A1 3528/4885MAPT 4536/4885SMN1; SMN2 3946/4885 |
| US-20090198053-A1 | Pyrazine Derivatives and Uses Thereof in Renal Monitoring | GLS, CYP3A5, PYCR1 | ALDH1A1 268/4885MAPT 4132/4885SMN1; SMN2 3945/4885 |
| US-20230158175-A1 | METHODS FOR RENAL FUNCTION DETERMINATION | GLS, SHBG, OGFR | ALDH1A1 1776/4885MAPT 3918/4885SMN1; SMN2 2715/4885 |
| US-20100233091-A1 | Pyrazine Derivatives with Extended Conjugation and Methods of Using the same in Optical Applications | CYP3A5, PAICS, CYP3A43 | ALDH1A1 320/4885MAPT 468/4885SMN1; SMN2 3290/4885 |
| US-12303570-B2 | Compositions and methods for assessing eye vasculature | LIPG, FLT4, FABP3 | ALDH1A1 1933/4885MAPT 2840/4885SMN1; SMN2 4165/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.