Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA1 | P56199 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 7/20 | 0.45 |
| ▸ | MMP1 | P03956 | 6/20 | 0.45 |
| ▸ | MMP9 | P14780 | 6/20 | 0.45 |
| ▸ | MMP13 | P45452 | 6/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | MMP8 | P22894 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.44 |
| ▸ | MMP3 | P08254 | 4/20 | 0.43 |
| ▸ | MMP7 | P09237 | 4/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MMP14 | P50281 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5899488 | 0.89 | KAT6A (0.49) | MMP2MMP1MMP9MMP13CA1 | |
| SCHEMBL5899419 | 0.87 | ALDH1A1 (0.49) | MMP2MMP1MMP9MMP13CA1 | |
| SCHEMBL5899417 | 0.87 | ADAMTS4 (0.50) | MMP2MMP1MMP9MMP13MMP8 | |
| SCHEMBL5899422 | 0.85 | FLT1 (0.57) | MMP2MMP1MMP9MMP13CA1 | |
| SCHEMBL5899495 | 0.85 | ALDH1A1 (0.50) | CA1CA2ALDH1A1 | |
| SCHEMBL5899456 | 0.83 | MMP2 (0.59) | MMP2MMP1MMP9MMP13KAT6A | |
| SCHEMBL14676363 | 0.83 | MMP2 (0.52) | MMP2MMP1MMP9MMP13CA1 | |
| SCHEMBL5899452 | 0.81 | KAT6A (0.48) | CA2KAT6AALDH1A1 | |
| SCHEMBL5899486 | 0.80 | KAT6A (0.57) | KAT6AALDH1A1 | |
| SCHEMBL5899671 | 0.79 | ACLY (0.44) | KAT6AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060025445-A1 | 11-Beta HSD1 inhibitors | WYETH | 2006-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060025445-A1 | 11-Beta HSD1 inhibitors | HSD11B1, HSD11B2, HSD3B1 | ITGA1 3934/4885MMP2 1212/4885MMP1 369/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.