Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT6A | Q92794 | 5/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MMP12 | P39900 | 1/20 | 0.45 |
| ▸ | ACLY | P53396 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5899429 | 0.88 | KAT6A (0.68) | KAT6AKMT2AALDH1A1MEP1BAKR1C3 | |
| SCHEMBL5320466 | 0.86 | ALDH1A1 (0.60) | KAT6ARECQLKMT2AMEN1NPC1 | |
| SCHEMBL5899491 | 0.85 | KAT6A (0.62) | KAT6ANPC1RAB9AALDH1A1GAA | |
| SCHEMBL5899544 | 0.84 | KAT6A (0.58) | KAT6AKMT2AMEN1ALDH1A1MEP1B | |
| SCHEMBL28531984 | 0.78 | ALDH1A1 (0.58) | KAT6AKMT2AMEN1ALDH1A1NPSR1 | |
| SCHEMBL23014361 | 0.77 | KAT6A (0.58) | KAT6AKMT2AMEN1ALDH1A1MEP1B | |
| SCHEMBL5899482 | 0.77 | L3MBTL1 (0.60) | KAT6AKMT2AMEN1ALDH1A1MEP1B | |
| SCHEMBL5899737 | 0.77 | MMP1 (0.63) | KAT6AKMT2AMEN1ALDH1A1MEP1B | |
| SCHEMBL5320463 | 0.77 | ITGAV (0.51) | KAT6AKMT2AMEN1NPC1RAB9A | |
| SCHEMBL754844 | 0.77 | KMT2A (0.56) | KAT6ARECQLKMT2AMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060025445-A1 | 11-Beta HSD1 inhibitors | WYETH | 2006-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060025445-A1 | 11-Beta HSD1 inhibitors | HSD11B1, HSD11B2, HSD3B1 | KAT6A 2440/4885RECQL 3378/4885KMT2A 1509/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.