Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.55 |
| ▸ | PLIN1 | O60240 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | RECQL | P46063 | 2/20 | 0.55 |
| ▸ | PLIN5 | Q00G26 | 2/20 | 0.55 |
| ▸ | ABHD5 | Q8WTS1 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | F3 | P13726 | 2/20 | 0.55 |
| ▸ | TNKS | O95271 | 1/20 | 0.55 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.55 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.55 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.55 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL6578283 | 0.98 | MAPT (0.57) | MAPTHDAC3HDAC4HDAC1HDAC2 | |
| SCHEMBL15120 | 0.82 | MAPT (0.61) | MAPTHDAC3HDAC4HDAC1HDAC2 | |
| SCHEMBL376003 | 0.82 | MAPT (0.61) | MAPTHDAC3HDAC4HDAC1HDAC2 | |
| Ammonia Solution, Strong SCHEMBL5175448 | 0.80 | MAPT (0.59) | MAPTHDAC3HDAC4HDAC1HDAC2 | |
| SCHEMBL3052516 | 0.80 | MAPT (0.59) | MAPTHDAC3HDAC4HDAC1HDAC2 | |
| SCHEMBL16268784 | 0.80 | MAPT (0.59) | MAPTHDAC3HDAC4HDAC1HDAC2 | |
| SCHEMBL3052514 | 0.80 | MAPT (0.59) | MAPTHDAC3HDAC4HDAC1HDAC2 | |
| SCHEMBL28287153 | 0.80 | MAPT (0.59) | MAPTHDAC3HDAC4HDAC1HDAC2 | |
| Cinnamic Acid SCHEMBL361738 | 0.79 | MAPT (0.64) | MAPTHDAC3HDAC4HDAC1HDAC2 | |
| Cinnamic Acid SCHEMBL123136 | 0.79 | MAPT (0.64) | MAPTHDAC3HDAC4HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11084987-B2 | Demulsifiers for separation of water from oil and preparation thereof | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2021-08-10 | — | — | US | disclosed |
| US-10655073-B2 | — | — | 2020-05-19 | — | — | US | disclosed |
| US-20170327753-A1 | Demulsifiers for Separation of Water from Oil and Preparation Thereof | OIL AND NATURAL GAS CORPORATION LTD. (IN) | 2017-11-16 | — | — | US | disclosed |
| WO-2016084104-A1 | DEMULSIFIERS FOR SEPARATION OF WATER FROM OIL AND PREPARATION THEREOF | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2016-06-02 | — | — | WO | disclosed |
| US-20060140898-A1 | Use of a combination of at least one associated polymer and at least one amphiphilic diblock copolymer for thickening cosmetic compositions | L'OREAL S.A. (FR) | 2006-06-29 | — | — | US | disclosed |
| US-6833129-B2 | Oligoesters obtained by condensation of one or more dicarboxylic acids or esters and one or more polyhydric alcohols | CLARIANT GMBH (DE) | 2004-12-21 | — | — | US | disclosed |
| EP-0364027-A2 | Bleaching and detergent composition | UNILEVER N.V. (NL) | 1990-04-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060140898-A1 | Use of a combination of at least one associated polymer and at least one amphiphilic diblock copolymer for thickening cosmetic compositions | PCNA, FAM83B, BRCA1 | MAPT 4355/4885HDAC3 4743/4885HDAC4 4636/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.