SCHEMBL5952291

SCHEMBL5952291

OCCC(OOB(O)c1ccccc1)OB(O)c1ccccc1

nearest known ligand 0.32

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CA4 P22748 1/20 0.32
CA6 P23280 1/20 0.32
CA5A P35218 1/20 0.32
CA7 P43166 1/20 0.32
ENPP2 Q13822 1/20 0.32
CA14 Q9ULX7 1/20 0.32
CA5B Q9Y2D0 1/20 0.32
PCSK9 Q8NBP7 1/20 0.32
ORAI1 Q96D31 1/20 0.32
ORAI2 Q96SN7 1/20 0.32
ORAI3 Q9BRQ5 1/20 0.32
TRPV6 Q9H1D0 1/20 0.32
TDP1 Q9NUW8 1/20 0.31
TRPA1 O75762 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1491912 0.76 ORAI1 (0.37) CA4CA6CA5ACA7ENPP2
SCHEMBL1429795 0.70 TRPV6 (0.41) CA4CA6CA5ACA7ENPP2
SCHEMBL15577145 0.70 TRPV6 (0.41) CA4CA6CA5ACA7ENPP2
SCHEMBL1138975 0.68 ALDH1A1 (0.42) CA4CA6CA5ACA7ENPP2
SCHEMBL28745155 0.66 TRPV6 (0.37) CA4CA6CA5ACA7ENPP2
SCHEMBL28745277 0.66 ORAI1 (0.37) CA4CA6CA5ACA7ENPP2
SCHEMBL1226528 0.65 TRPV6 (0.44) CA4CA6CA5ACA7ENPP2
SCHEMBL15570627 0.65 TRPV6 (0.44) CA4CA6CA5ACA7ENPP2
SCHEMBL117263 0.64 ALDH1A1 (0.45) CA4CA6CA5ACA7ENPP2
Ethylene Glycol SCHEMBL28307523 0.64 ENPP2 (0.42) CA4CA6CA5ACA7ENPP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230210790-A1 GEL FOR USE IN GASTROINTESTINAL ENDOSCOPY AND ENDODERMAL, EPIDERMAL, AND OTHER MUCOSAL USES THE JOHNS HOPKINS UNIVERSTY 2023-07-06 US claimed
EP-4157998-A1 GEL FOR USE IN GASTROINTESTINAL ENDOSCOPY AND ENDODERMAL, EPIDERMAL, AND OTHER MUCOSAL USES The Johns Hopkins University (US) 2023-04-05 EP claimed
EP-3344232-B1 MICELLES FOR MUCOADHESIVE DRUG DELIVERY UNIV MCMASTER (CA) 2022-01-26 EP claimed
US-10611908-B2 Micelles for mucoadhesive drug delivery MCMASTER UNIVERSITY (CA) 2020-04-07 US claimed
US-20180265694-A1 Micelles for Mucoadhesive Drug Delivery MCMASTER UNIVERSITY (CA) 2018-09-20 US claimed
EP-3344232-A1 MICELLES FOR MUCOADHESIVE DRUG DELIVERY Mcmaster University (CA) 2018-07-11 EP claimed
WO-2017035656-A1 MICELLES FOR MUCOADHESIVE DRUG DELIVERY MCMASTER UNIVERSITY (CA) 2017-03-09 WO claimed
US-20240229131-A1 TRANSITION-METAL CATALYST COMPOSITIONS AND METHODS FOR SEQUENCING BY SYNTHESIS ILLUMINA, INC. 2024-07-11 US disclosed
WO-2024145154-A1 METHODS OF SEQUENCING USING 3´ ALLYL BLOCKED NUCLEOTIDES ILLUMINA, INC. (US) 2024-07-04 WO disclosed
US-20240218443-A1 METHODS OF SEQUENCING USING 3' BLOCKED NUCLEOTIDES ILLUMINA, INC. 2024-07-04 US disclosed
US-20240209015-A1 METHODS OF SEQUENCING USING 3' BLOCKED NUCLEOTIDES ILLUMINA, INC. 2024-06-27 US disclosed
US-20240182963-A1 METHODS OF SEQUENCING USING 3' BLOCKED NUCLEOTIDES ILLUMINA, INC. 2024-06-06 US disclosed
US-20230210790-A1 GEL FOR USE IN GASTROINTESTINAL ENDOSCOPY AND ENDODERMAL, EPIDERMAL, AND OTHER MUCOSAL USES THE JOHNS HOPKINS UNIVERSTY 2023-07-06 US disclosed
EP-2986666-A1 METHOD OF MANUFACTURING NON-FIRED TYPE ELECTRODE E. I. du Pont de Nemours and Company (US) 2016-02-24 EP disclosed
WO-2014172137-A1 METHOD OF MANUFACTURING NON-FIRED TYPE ELECTRODE E. I. DU PONT DE NEMOURS AND COMPANY (US) 2014-10-23 WO disclosed
US-20140306165-A1 METHOD OF MANUFACTURING NON-FIRING TYPE ELECTRODE E I DU PONT DE NEMOURS AND COMPANY (US) 2014-10-16 US disclosed
US-7038070-B2 Preparation of preparing substituted indanones BASELL POLYOLEFINE GMBH (DE) 2006-05-02 US disclosed
US-6963017-B2 Preparation of preparing substituted indanones BASELL POLYOLEFINE GMBH (DE) 2005-11-08 US disclosed
US-20050033076-A1 Preparation of preparing substituted indanones EQUISTAR CHEMICALS, LP 2005-02-10 US disclosed
US-20030009046-A1 Preparation of preparing substituted indanones EQUISTAR CHEMICALS, LP 2003-01-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050033076-A1 Preparation of preparing substituted indanones CYP1A2, CYP2J2, IDH3A CA4 4167/4885CA6 3014/4885CA5A 3044/4885
US-20240182963-A1 METHODS OF SEQUENCING USING 3' BLOCKED NUCLEOTIDES NT5C3B, RNGTT, ALKBH1 CA4 2300/4885CA6 2289/4885CA5A 1555/4885
US-20030009046-A1 Preparation of preparing substituted indanones CYP1A2, CYP1B1, CYP1A1 CA4 4047/4885CA6 2951/4885CA5A 3066/4885
US-20240209015-A1 METHODS OF SEQUENCING USING 3' BLOCKED NUCLEOTIDES RNGTT, NT5C3B, NSUN2 CA4 3724/4885CA6 3531/4885CA5A 1925/4885
US-20230210790-A1 GEL FOR USE IN GASTROINTESTINAL ENDOSCOPY AND ENDODERMAL, EPIDERMAL, AND OTHER MUCOSAL USES EPX, EPCAM, ELANE CA4 3103/4885CA6 2295/4885CA5A 4786/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.