Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PCSK9 | Q8NBP7 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.35 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.35 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | LDLR | P01130 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 2/20 | 0.34 |
| ▸ | HPGDS | O60760 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2753252 | 0.71 | BRD9 (0.33) | BRD9 | |
| SCHEMBL2751459 | 0.70 | METAP2 (0.33) | — | |
| SCHEMBL2750412 | 0.70 | AR (0.36) | CYP1A2CYP3A4NPC1RAB9AALDH1A1 | |
| SCHEMBL2752728 | 0.70 | SMN1; SMN2 (0.44) | CYP1A2SMN1; SMN2 | |
| SCHEMBL2752751 | 0.70 | — | — | |
| SCHEMBL2750000 | 0.68 | — | — | |
| SCHEMBL2752335 | 0.68 | ADRA2A (0.35) | CYP1A2CYP2D6 | |
| SCHEMBL10480724 | 0.68 | PCSK9 (0.47) | PCSK9KMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL822673 | 0.67 | PCSK9 (0.68) | PCSK9KMT2ACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL6444709 | 0.67 | PCSK9 (0.73) | PCSK9KMT2ACYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060004218-A1 | Binuclear transition metal complexes | LANXESS DEUTSCHLAND GMBH (DE) | 2006-01-05 | — | — | US | disclosed |
| US-20050282982-A1 | Amido complexes of vanadium for olefin polymerization | LANXESS DEUTSCHLAND GMBH (DE) | 2005-12-22 | — | — | US | disclosed |
| EP-1284270-B1 | Vanadium-Imido-Phosphoraniminato complexes for olefin polymerisation | BAYER AG (DE) | 2005-06-29 | — | — | EP | disclosed |
| US-6846769-B2 | Vanadium-imido-phosphoraneiminato complexes for the polymerization of olefins | BAYER AKTIENGESELLSCHAFT (DE) | 2005-01-25 | — | — | US | disclosed |
| US-20030114675-A1 | Vanadium-imido-phosphoraneiminato complexes for the polymerization of olefins | LANXESS DEUTSCHLAND GMBH (DE) | 2003-06-19 | — | — | US | disclosed |
| EP-1284270-A1 | Vanadium-Imido-Phosphoraniminato complexes for olefin polymerisation | BAYER AG (DE) | 2003-02-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030114675-A1 | Vanadium-imido-phosphoraneiminato complexes for the polymerization of olefins | MVD, PPIP5K2, PI4KA | PCSK9 4823/4885KMT2A 3368/4885CYP1A2 3133/4885 |
| US-20050282982-A1 | Amido complexes of vanadium for olefin polymerization | NOX4, NOXO1, COG4 | PCSK9 2525/4885KMT2A 3469/4885CYP1A2 1073/4885 |
| US-20060004218-A1 | Binuclear transition metal complexes | PICALM, PCBP1, AP1M1 | PCSK9 4386/4885KMT2A 2716/4885CYP1A2 2691/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.