Known targets — ChEMBL curated mechanism
ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3CHRM1CHRM2CHRM3CHRM4ESR1ESR2GABRA1GABRB1GABRG2GBA1HRH1HTR1DHTR2AOPRD1OPRK1OPRM1SLC6A2SLC6A3TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Cadaverine Tartrate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 known ✓ | P08173 | 1/20 | 0.41 |
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | NAAA | Q02083 | 1/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cadaverine Tartrate SCHEMBL5987469 | 0.93 | FAAH (0.45) | THRATHRBNAAACHRM2CHRM4 | |
| SCHEMBL13601609 | 0.90 | NAAA (0.53) | THRATHRBNAAANPC1TP53 | |
| SCHEMBL6476420 | 0.90 | NAAA (0.53) | THRATHRBNAAANPC1TP53 | |
| SCHEMBL27613309 | 0.87 | THRA (0.40) | THRATHRBNAAACHRM2CHRM4 | |
| SCHEMBL10852328 | 0.84 | THRA (0.47) | THRATHRBNAAANPC1TP53 | |
| SCHEMBL11855822 | 0.84 | NAAA (0.60) | THRATHRBNAAANPSR1MAPT | |
| SCHEMBL27613308 | 0.83 | NAAA (0.43) | THRATHRBNAAANPC1TP53 | |
| SCHEMBL5990174 | 0.83 | FAAH (0.52) | THRATHRBNAAANPC1TP53 | |
| SCHEMBL12881348 | 0.78 | GNAI3 (0.55) | THRATHRBNAAANPSR1MAPT | |
| SCHEMBL12772763 | 0.78 | GNAI3 (0.55) | THRATHRBNAAANPSR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060173053-A1 | Basic esters of fatty alcohols and their use as anti-inflammatory or immunomodulatory agents | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2006-08-03 | — | — | US | claimed |
| EP-1551495-A2 | BASIC ESTERS OF FATTY ALCOHOLS AND THEIR USE AS ANTI-INFLAMMATORY OR IMMUNOMODULATORY AGENTS | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2005-07-13 | — | — | EP | claimed |
| WO-2004032824-A2 | BASIC ESTERS OF FATTY ALCOHOLS AND THEIR USE AS ANTI-INFLAMMATORY OR IMMUNOMODULATORY AGENTS | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2004-04-22 | — | — | WO | claimed |
| US-8987263-B2 | Basic esters of fatty alcohols and their use as anti-inflammatory or immunomodulatory agents | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2015-03-24 | — | — | US | disclosed |
| US-20060173053-A1 | Basic esters of fatty alcohols and their use as anti-inflammatory or immunomodulatory agents | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2006-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060173053-A1 | Basic esters of fatty alcohols and their use as anti-inflammatory or immunomodulatory agents | ALOX12, ALOX15, ALOX15B | CHRM2 284/4885CHRM4 294/4885CHRM1 191/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.