SCHEMBL5997004

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5996999	1.00	RORC (0.55)	RORCMAPTTP53ALDH1A1CYP1A2
	SCHEMBL5997656	0.83	RORC (0.57)	RORCMAPTTP53ALDH1A1CYP1A2
	SCHEMBL4704464	0.82	RAB9A (0.62)	RORCMAPTTP53ALDH1A1CYP1A2
	SCHEMBL5997266	0.82	MAPT (0.66)	RORCMAPTTP53ALDH1A1CYP1A2
	SCHEMBL13954541	0.78	RORC (0.46)	RORCMAPTTP53ALDH1A1CYP1A2
	SCHEMBL13447018	0.74	ROCK2 (0.34)	RORCMAPTTP53ALDH1A1KDM4E
	SCHEMBL5996876	0.72	RORC (0.48)	RORCMAPTTP53ALDH1A1CYP1A2
	SCHEMBL13447078	0.72	SYK (0.39)	TP53ALDH1A1L3MBTL1NPC1RAB9A
	SCHEMBL13447076	0.72	SYK (0.39)	TP53ALDH1A1L3MBTL1NPC1RAB9A
	SCHEMBL4704685	0.71	MAPT (0.61)	RORCMAPTTP53ALDH1A1CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.