Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 10/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 6/20 | 0.49 |
| ▸ | RAB9A | P51151 | 6/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | USP28 | Q96RU2 | 4/20 | 0.46 |
| ▸ | USP25 | Q9UHP3 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4704464 | 0.84 | RAB9A (0.62) | RORCMAPTTP53ALDH1A1KDM4E | |
| SCHEMBL5996999 | 0.83 | RORC (0.55) | RORCMAPTTP53ALDH1A1KDM4E | |
| SCHEMBL5997004 | 0.83 | RORC (0.55) | RORCMAPTTP53ALDH1A1KDM4E | |
| SCHEMBL5997266 | 0.83 | MAPT (0.66) | RORCMAPTTP53ALDH1A1KDM4E | |
| SCHEMBL13154849 | 0.82 | ALDH1A1 (0.45) | RORCMAPTTP53ALDH1A1KDM4E | |
| SCHEMBL13954541 | 0.77 | RORC (0.46) | RORCMAPTTP53ALDH1A1KDM4E | |
| SCHEMBL13447005 | 0.74 | NAMPT (0.39) | RORCMAPTTP53ALDH1A1KDM4E | |
| SCHEMBL5996876 | 0.74 | RORC (0.48) | RORCMAPTTP53ALDH1A1KDM4E | |
| SCHEMBL22690991 | 0.72 | MAPT (0.61) | RORCMAPTTP53ALDH1A1KDM4E | |
| SCHEMBL13154827 | 0.72 | MAPT (0.46) | RORCMAPTTP53ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060247320-A1 | Compounds for inhibiting KSP kinesin activity | SCHERING CORPORATION | 2006-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060247320-A1 | Compounds for inhibiting KSP kinesin activity | KIFC1, KIF5B, KIF2C | RORC 2343/4885MAPT 434/4885TP53 580/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.