Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 1/20 | 0.44 |
| ▸ | TUBB | P07437 | 1/20 | 0.44 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.44 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.44 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.44 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.44 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.44 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.44 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.44 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.44 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.44 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.44 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.44 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.44 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.44 |
| ▸ | GABRP | O00591 | 4/20 | 0.40 |
| ▸ | GABRD | O14764 | 4/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 4/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3247150 | 0.83 | TUBB4A (0.42) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL6003653 | 0.80 | GPR84 (0.42) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL3250264 | 0.69 | MTNR1A (0.47) | MEN1KMT2AMTNR1A | |
| SCHEMBL8541224 | 0.69 | CYP19A1 (0.53) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL5657449 | 0.69 | DHFR (0.48) | MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL27929617 | 0.68 | NQO2 (0.61) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL3246827 | 0.67 | DHFR (0.46) | MEN1KMT2A | |
| SCHEMBL6716653 | 0.66 | MEN1 (0.50) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL4629902 | 0.65 | GPR84 (0.57) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL6719869 | 0.65 | PLA2G4A (0.58) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1651639-A1 | BENZOFURAN DERIVATIVES AND THEIR USE IN THE TREATMENT OF MICROBIAL INFECTIONS | Arpida AG, (CH) | 2006-05-03 | — | — | EP | claimed |
| WO-2005005418-A1 | BENZOFURAN DERIVATIVES AND THEIR USE IN THE TREATMENT OF MICROBIAL INFECTIONS | ARPIDA AG (CH) | 2005-01-20 | — | — | WO | claimed |
| EP-1651639-A1 | BENZOFURAN DERIVATIVES AND THEIR USE IN THE TREATMENT OF MICROBIAL INFECTIONS | Arpida AG, (CH) | 2006-05-03 | — | — | EP | disclosed |
| WO-2005005418-A1 | BENZOFURAN DERIVATIVES AND THEIR USE IN THE TREATMENT OF MICROBIAL INFECTIONS | ARPIDA AG (CH) | 2005-01-20 | — | — | WO | disclosed |