Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.52 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 8/20 | 0.46 |
| ▸ | HTR1A | P08908 | 2/20 | 0.46 |
| ▸ | HTR1D | P28221 | 2/20 | 0.46 |
| ▸ | HTR1B | P28222 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 3/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6005314 | 0.83 | HRH3 (0.49) | SLC6A2SLC6A4MAOBHTR1AHRH3 | |
| SCHEMBL6004162 | 0.81 | ALDH1A1 (0.36) | — | |
| SCHEMBL6004262 | 0.81 | ALDH1A1 (0.36) | HTR1ACYP2D6 | |
| SCHEMBL6002950 | 0.81 | MET (0.44) | ACHEMAOA | |
| SCHEMBL6004285 | 0.80 | CYP3A4 (0.46) | MAOA | |
| SCHEMBL6005251 | 0.78 | PDE2A (0.39) | — | |
| SCHEMBL6004932 | 0.77 | IRAK4 (0.39) | MAOBMAOA | |
| SCHEMBL6004922 | 0.77 | SLC22A12 (0.39) | MAOA | |
| SCHEMBL6005366 | 0.73 | PDGFRB (0.36) | — | |
| SCHEMBL6004251 | 0.73 | TGFBR1 (0.39) | CYP2D6ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1724268-A1 | COMPOUND HAVING TGF-BETA INHIBITORY ACTIVITY AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | KIRIN BEER KABUSHIKI KAISHA (JP) | 2006-11-22 | — | — | EP | disclosed |