Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | PARP15 | Q460N3 | 4/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 4/20 | 0.37 |
| ▸ | NOS3 | P29474 | 2/20 | 0.36 |
| ▸ | NOS1 | P29475 | 2/20 | 0.36 |
| ▸ | FLT3 | P36888 | 2/20 | 0.35 |
| ▸ | PDE2A | O00408 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | KIT | P10721 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6004333 | 0.88 | PDGFRA (0.42) | FLT3KIT | |
| SCHEMBL6004162 | 0.84 | ALDH1A1 (0.36) | — | |
| SCHEMBL6004922 | 0.82 | SLC22A12 (0.39) | MAOAPDE2A | |
| SCHEMBL6004262 | 0.82 | ALDH1A1 (0.36) | — | |
| SCHEMBL6005366 | 0.82 | PDGFRB (0.36) | — | |
| SCHEMBL6004285 | 0.81 | CYP3A4 (0.46) | MAOA | |
| SCHEMBL6005251 | 0.81 | PDE2A (0.39) | PDE2A | |
| SCHEMBL6005281 | 0.80 | DDR2 (0.34) | — | |
| SCHEMBL6004251 | 0.78 | TGFBR1 (0.39) | — | |
| SCHEMBL6004825 | 0.77 | SLC6A2 (0.52) | MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1724268-A1 | COMPOUND HAVING TGF-BETA INHIBITORY ACTIVITY AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | KIRIN BEER KABUSHIKI KAISHA (JP) | 2006-11-22 | — | — | EP | disclosed |