Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKB | O14920 | 2/20 | 0.39 |
| ▸ | MET | P08581 | 11/20 | 0.39 |
| ▸ | KDR | P35968 | 8/20 | 0.39 |
| ▸ | MST1R | Q04912 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 2/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | FLT1 | P17948 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6005342 | 0.83 | MET (0.42) | METKDRNPC1MAPT | |
| SCHEMBL6004276 | 0.80 | LMNA (0.39) | KDRNPC1SMN1; SMN2 | |
| SCHEMBL6004327 | 0.80 | TOP1 (0.42) | NPC1MAPTRAB9A | |
| SCHEMBL6004803 | 0.76 | FGFR2 (0.36) | KDRNPC1 | |
| SCHEMBL6004795 | 0.76 | FGFR2 (0.36) | METKDRMST1RNPC1 | |
| SCHEMBL6002787 | 0.76 | CCNC (0.39) | IKBKBNPC1 | |
| SCHEMBL6005302 | 0.76 | DHODH (0.39) | — | |
| SCHEMBL3895779 | 0.76 | FGFR2 (0.53) | KDREGFR | |
| SCHEMBL6005306 | 0.75 | MAPK14 (0.34) | METMST1RNPC1 | |
| SCHEMBL6004171 | 0.75 | NPC1 (0.33) | METKDRMST1RNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1724268-A1 | COMPOUND HAVING TGF-BETA INHIBITORY ACTIVITY AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | KIRIN BEER KABUSHIKI KAISHA (JP) | 2006-11-22 | — | — | EP | disclosed |