Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 9/20 | 0.42 |
| ▸ | KDR | P35968 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 1/20 | 0.31 |
| ▸ | TOP1 | P11387 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6005337 | 0.84 | ALDH1A1 (0.38) | METKDRADORA2AADORA1MAPT | |
| SCHEMBL6005041 | 0.83 | IKBKB (0.39) | METKDRNPC1MAPT | |
| SCHEMBL6004327 | 0.81 | TOP1 (0.42) | NPC1PDGFRBPDGFRAMAPTDHODH | |
| SCHEMBL6004276 | 0.81 | LMNA (0.39) | KDRNPC1ADORA2APDGFRBPDGFRA | |
| SCHEMBL6004803 | 0.77 | FGFR2 (0.36) | KDRNPC1ADORA2AADORA1PDGFRB | |
| SCHEMBL6002787 | 0.77 | CCNC (0.39) | NPC1DHODH | |
| SCHEMBL6004795 | 0.77 | FGFR2 (0.36) | METKDRNPC1DHODHTOP1 | |
| SCHEMBL6005302 | 0.76 | DHODH (0.39) | DHODHTOP1 | |
| SCHEMBL3895779 | 0.76 | FGFR2 (0.53) | KDRPDGFRBPDGFRA | |
| SCHEMBL6005306 | 0.76 | MAPK14 (0.34) | METNPC1PDGFRBPDGFRADHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1724268-A1 | COMPOUND HAVING TGF-BETA INHIBITORY ACTIVITY AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | KIRIN BEER KABUSHIKI KAISHA (JP) | 2006-11-22 | — | — | EP | disclosed |