Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MET | P08581 | 4/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.34 |
| ▸ | PDE4A | P27815 | 2/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.34 |
| ▸ | NR2C2 | P49116 | 1/20 | 0.33 |
| ▸ | TAB1 | Q15750 | 1/20 | 0.33 |
| ▸ | SYK | P43405 | 1/20 | 0.33 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.33 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.33 |
| ▸ | AXL | P30530 | 1/20 | 0.33 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6005342 | 0.84 | MET (0.42) | MAPTMETADORA2AADORA1KDR | |
| SCHEMBL6004268 | 0.83 | ALDH1A1 (0.58) | ALDH1A1HTTNR2C2TAB1KIT | |
| SCHEMBL13605215 | 0.80 | LCK (0.49) | METAURKBEGFRKDRKDM1A | |
| SCHEMBL6004712 | 0.80 | PRNP (0.43) | ALDH1A1MAPTHTTAURKBMKNK2 | |
| SCHEMBL6003009 | 0.80 | MAT2A (0.43) | ALDH1A1MAPTAURKBEGFRDHODH | |
| SCHEMBL6004877 | 0.79 | KDM4E (0.46) | ALDH1A1L3MBTL1EGFRKDRFLT3 | |
| SCHEMBL6004750 | 0.77 | MRGPRX1 (0.53) | ALDH1A1MAPTHTTMETADORA2A | |
| SCHEMBL6004312 | 0.74 | MRGPRX1 (0.56) | MAPTHTT | |
| SCHEMBL6004714 | 0.72 | TGFBR1 (0.46) | METADORA2AADORA1EGFRKIT | |
| SCHEMBL6005041 | 0.70 | IKBKB (0.39) | MAPTMETEGFRKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1724268-A1 | COMPOUND HAVING TGF-BETA INHIBITORY ACTIVITY AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | KIRIN BEER KABUSHIKI KAISHA (JP) | 2006-11-22 | — | — | EP | disclosed |