Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBX7 | O95931 | 2/20 | 0.44 |
| ▸ | CDYL2 | Q8N8U2 | 2/20 | 0.44 |
| ▸ | CDYL | Q9Y232 | 2/20 | 0.44 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | L3MBTL3 | Q96JM7 | 8/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.41 |
| ▸ | MBTD1 | Q05BQ5 | 5/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | TP53BP1 | Q12888 | 3/20 | 0.41 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.40 |
| ▸ | L3MBTL4 | Q8NA19 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6016055 | 0.82 | CBX7 (0.55) | CBX7CDYL2CDYLCDY1; CDY1BACHE | |
| SCHEMBL6015703 | 0.80 | REN (0.39) | POLBKMT2A | |
| SCHEMBL6015675 | 0.78 | TDP1 (0.46) | L3MBTL1POLBTSHRTDP1MEN1 | |
| SCHEMBL6015933 | 0.78 | HSD11B1 (0.43) | NPSR1GAATSHRKDM4EALDH1A1 | |
| SCHEMBL6015646 | 0.68 | KDM4E (0.47) | CBX7CDYL2CDYLCDY1; CDY1BACHE | |
| SCHEMBL3774050 | 0.66 | KDM4E (0.73) | CBX7CDYL2CDYLCDY1; CDY1BACHE | |
| SCHEMBL6015693 | 0.66 | ALDH1A1 (0.41) | ACHECYP2C19GAAALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL3844455 | 0.65 | KDM4E (0.44) | CBX7CDYL2CDYLCDY1; CDY1BACHE | |
| SCHEMBL2831484 | 0.64 | C3AR1 (0.61) | L3MBTL3MAPTTDP1 | |
| Hydrochloric Acid SCHEMBL3847607 | 0.64 | L3MBTL3 (0.44) | CBX7CDYL2CDYLCDY1; CDY1BNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7049312-B1 | Benzothiazinone and benzoxazinone compounds | ABBOTT GMBH & CO. KG (DE) | 2006-05-23 | — | — | US | claimed |
| EP-1181282-A2 | BENZOTHIAZINONE AND BENZOXAZINONE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2002-02-27 | — | — | EP | claimed |
| WO-2000075139-A2 | BENZOTHIAZINONE AND BENZOXAZINONE COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2000-12-14 | — | — | WO | claimed |
| US-7049312-B1 | Benzothiazinone and benzoxazinone compounds | ABBOTT GMBH & CO. KG (DE) | 2006-05-23 | — | — | US | disclosed |