Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 known ✓ | Q9H244 | 1/20 | 0.40 |
| ▸ | RAD51 | Q06609 | 11/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 2/20 | 0.53 |
| ▸ | LTA | P01374 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | HTR6 | P50406 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MPO | P05164 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31389378 | 1.00 | RAD51 (0.58) | RAD51ALDH1A1CYP3A4KDM4EUSP2 | |
| SCHEMBL29692691 | 1.00 | RAD51 (0.58) | RAD51ALDH1A1CYP3A4KDM4EUSP2 | |
| SCHEMBL6397268 | 1.00 | RAD51 (0.58) | RAD51ALDH1A1CYP3A4KDM4EUSP2 | |
| Lithium Ion SCHEMBL8492595 | 0.96 | RAD51 (0.58) | RAD51ALDH1A1CYP3A4KDM4EUSP2 | |
| SCHEMBL5858436 | 0.92 | RAD51 (0.50) | RAD51ALDH1A1CYP3A4KDM4EUSP2 | |
| SCHEMBL5754531 | 0.92 | RAD51 (0.50) | RAD51ALDH1A1CYP3A4KDM4EUSP2 | |
| SCHEMBL5749384 | 0.89 | RAD51 (0.51) | RAD51ALDH1A1CYP3A4KDM4EUSP2 | |
| SCHEMBL2111817 | 0.87 | RAD51 (0.44) | RAD51ALDH1A1CYP3A4KDM4EUSP2 | |
| SCHEMBL6050517 | 0.86 | RAD51 (0.66) | RAD51ALDH1A1CYP3A4KDM4EUSP2 | |
| SCHEMBL2391195 | 0.86 | RAD51 (0.66) | RAD51ALDH1A1CYP3A4KDM4EUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 82 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115228291-B | Anti-pollution, antibacterial and high-flux reverse osmosis membrane and preparation method and application thereof | 万华化学集团股份有限公司 | 2024-06-25 | — | — | CN | claimed |
| CN-115228291-A | Anti-pollution, antibacterial and large-flux reverse osmosis membrane and preparation method and application thereof | 万华化学集团股份有限公司 | 2022-10-25 | — | — | CN | claimed |
| WO-2017072788-A1 | IMPROVED OPTICAL BRIGHTENING AGENT FOR DETERGENT FORMULATIONS AND A PROCESS FOR PREPARING THE SAME | DEEPAK NITRITE LIMITED (IN) | 2017-05-04 | — | — | WO | claimed |
| EP-0977545-B1 | THE USE OF 1-SUBSTITUTED ISATINS TO DYE FIBERS CONTAINING KERATIN | HENKEL KGAA (DE) | 2005-02-16 | — | — | EP | claimed |
| EP-1037586-B1 | UTILIZATION OF ONIUM ALDEHYDES AND ONIUM KETONES FOR DYING FIBERS CONTAINING KERATIN | HENKEL KGAA (DE) | 2004-12-22 | — | — | EP | claimed |
| US-6371993-B1 | HAIR DYES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2002-04-16 | — | — | US | claimed |
| US-4299910-A | AMINO AND/OR NITRO-SUBSTITUTED STILBENE DISULFONIC ACIDS | RCA CORPORATION (US) | 1981-11-10 | — | — | US | claimed |
| US-3936497-A | HYDROGENATION OF DINITRO WITH NICKEL CATALYST | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1976-02-03 | — | — | US | claimed |
| JP-56019009-A | — | — | None | — | — | JP | disclosed |
| CN-115228291-B | Anti-pollution, antibacterial and high-flux reverse osmosis membrane and preparation method and application thereof | 万华化学集团股份有限公司 | 2024-06-25 | — | — | CN | disclosed |
| CN-115228291-A | Anti-pollution, antibacterial and large-flux reverse osmosis membrane and preparation method and application thereof | 万华化学集团股份有限公司 | 2022-10-25 | — | — | CN | disclosed |
| WO-2021106798-A1 | POLARIZED LIGHT-EMITTING ELEMENT, POLARIZED LIGHT-EMITTING PLATE, AND DISPLAY DEVICE | 日本化薬株式会社 | 2021-06-03 | — | — | WO | disclosed |
| EP-3395911-A1 | COLORING COMPOSITION, INKJET INK, AND PRINTING METHOD | FUJIFILM Corporation (JP) | 2018-10-31 | — | — | EP | disclosed |
| US-20180298196-A1 | COLORING COMPOSITION, INK JET INK, AND TEXTILE PRINTING METHOD | FUJIFILM CORPORATION (JP) | 2018-10-18 | — | — | US | disclosed |
| US-4005026-A | Detergent compositions containing novel crystalline forms of optical brighteners | STERLING DRUG INC. (US) | 1977-01-25 | — | — | US | disclosed |
| US-3970647-A | Bis-(triazinylamino)stilbene compounds | SANDOZ LTD. (CH) | 1976-07-20 | — | — | US | disclosed |
| US-3954740-A | Bis-s-triazinylamino-stilbene-2,2'-disulphonic acids, their manufacture and their use as optical brighteners | CIBA-GEIGY CORPORATION (US) | 1976-05-04 | — | — | US | disclosed |
| US-3951960-A | BIS-TRIAZINYLAMINOSTILBENE | STERLING DRUG INC. (US) | 1976-04-20 | — | — | US | disclosed |
| US-3936497-A | HYDROGENATION OF DINITRO WITH NICKEL CATALYST | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1976-02-03 | — | — | US | disclosed |
| US-3936497-A | HYDROGENATION OF DINITRO WITH NICKEL CATALYST | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1976-02-03 | — | — | US | disclosed |