Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KLK6 | Q92876 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6065131 | 0.88 | LMNA (0.40) | LMNAL3MBTL1ALDH1A1SMN1; SMN2CYP2C19 | |
| SCHEMBL6065771 | 0.82 | LMNA (0.35) | LMNAL3MBTL1TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL6066190 | 0.81 | SMN1; SMN2 (0.35) | LMNAKMT2AL3MBTL1SMN1; SMN2CYP2C19 | |
| SCHEMBL6558372 | 0.80 | POLB (0.43) | LMNAKMT2AMAPK1TSHRALDH1A1 | |
| SCHEMBL6065740 | 0.79 | F2 (0.41) | LMNAKMT2AALDH1A1SMN1; SMN2CYP2C19 | |
| SCHEMBL6065114 | 0.72 | PKM (0.49) | PKMLMNAKMT2AMAPK1L3MBTL1 | |
| SCHEMBL6065290 | 0.72 | DUT (0.30) | — | |
| SCHEMBL3112835 | 0.71 | MAPK1 (0.40) | PKMLMNAKMT2AMAPK1L3MBTL1 | |
| SCHEMBL6065016 | 0.70 | KMT2A (0.33) | PKMLMNAKMT2AMAPK1SMN1; SMN2 | |
| SCHEMBL6558343 | 0.70 | NPC1 (0.41) | LMNAKMT2AALDH1A1CYP1A2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1663245-A1 | CEPHEM COMPOUNDS | Astellas Pharma Inc. (JP) | 2006-06-07 | — | — | EP | disclosed |
| WO-2005027909-A1 | CEPHEM COMPOUNDS | ASTELLAS PHARMA INC. (JP) | 2005-03-31 | — | — | WO | disclosed |