SCHEMBL6065290

SCHEMBL6065290

Cc1n[nH]c(NC(c2ccccc2)(c2ccccc2)c2ccccc2)c1NC(=O)N(CCNC(c1ccccc1)(c1ccccc1)c1ccccc1)CCOC(N)=O

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
DUT P33316 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6065032 0.95 LMNA (0.31)
SCHEMBL6065097 0.72 PKM (0.45)
SCHEMBL6065131 0.71 LMNA (0.40)
SCHEMBL6066190 0.71 SMN1; SMN2 (0.35)
SCHEMBL6065740 0.69 F2 (0.41)
SCHEMBL6065016 0.68 KMT2A (0.33)
SCHEMBL6065771 0.66 LMNA (0.35)
SCHEMBL27641124 0.66 ACACB (0.30)
SCHEMBL6558372 0.62 POLB (0.43)
SCHEMBL6557414 0.62 MTNR1A (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1663245-A1 CEPHEM COMPOUNDS Astellas Pharma Inc. (JP) 2006-06-07 EP disclosed
WO-2005027909-A1 CEPHEM COMPOUNDS ASTELLAS PHARMA INC. (JP) 2005-03-31 WO disclosed