Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | ATM | Q13315 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.53 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.43 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.43 |
| ▸ | ALB | P02768 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | RARB | P10826 | 1/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1398573 | 0.85 | ATM (0.50) | TSHRATMMAPK1TDP1L3MBTL1 | |
| SCHEMBL3386532 | 0.82 | CA2 (0.45) | TSHRTDP1AKR1C3AKR1C2CYP2C9 | |
| SCHEMBL27367826 | 0.79 | TDP1 (0.48) | TSHRATMMAPK1TDP1L3MBTL1 | |
| SCHEMBL9493331 | 0.79 | SRC (0.54) | TSHRATMMAPK1TDP1L3MBTL1 | |
| SCHEMBL11476703 | 0.78 | LMNA (0.56) | TSHRATMMAPK1TDP1L3MBTL1 | |
| SCHEMBL11476706 | 0.78 | LMNA (0.56) | TSHRATMMAPK1TDP1L3MBTL1 | |
| SCHEMBL29390746 | 0.78 | PTGS2 (0.69) | TSHRAKR1C3AKR1C2CYP2C9ALDH1A1 | |
| SCHEMBL1512673 | 0.78 | PTGS2 (0.69) | TSHRAKR1C3AKR1C2CYP2C9ALDH1A1 | |
| SCHEMBL11260217 | 0.77 | L3MBTL1 (0.50) | TSHRATMMAPK1TDP1L3MBTL1 | |
| SCHEMBL11260212 | 0.77 | CYP2C9 (0.59) | TSHRATMMAPK1TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7109370-B2 | Substituted phenylketoenols | BAYER AKTIENGESELLSCHAFT (DE) | 2006-09-19 | — | — | US | disclosed |
| US-20050187111-A1 | Novel substituted phenylketoenols | HAGEMANN HERMANN (DE) | 2005-08-25 | — | — | US | disclosed |
| US-20040102327-A1 | Pesticides, herbicides; spiropyran-pyrroline-2-one deriva-tives | HAGEMANN HERMANN (DE) | 2004-05-27 | — | — | US | disclosed |
| US-6670488-B1 | N-(phenylacetyl)-4-amino-4-carboxyethyl-2-methyl -tetrahydropyran intermediate cyclizes to 3-(phenyl)-5,5-((2-ethyl)- ethylene oxyethyl)-pyrrolin-2-one-4-carboxylate herbicide | BAYER AKTIENGESELLSCHAFT (DE) | 2003-12-30 | — | — | US | disclosed |
| US-20030228984-A1 | Novel substituted phenylketoenols | HAGEMANN HERMANN (DE) | 2003-12-11 | — | — | US | disclosed |
| US-6608211-B1 | Pesticides and herbicides; well tolerated by plants | BAYER AKTIENGESELLSCHAFT (DE) | 2003-08-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030228984-A1 | Novel substituted phenylketoenols | AKR1A1, AKR1B1, AKR1C1 | TSHR 3204/4885ATM 3948/4885MAPK1 613/4885 |
| US-20050187111-A1 | Novel substituted phenylketoenols | PDHX, AKR1A1, AKR1B1 | TSHR 2943/4885ATM 3156/4885MAPK1 1632/4885 |
| US-20040102327-A1 | Pesticides, herbicides; spiropyran-pyrroline-2-one deriva-tives | PDHA1, PDHA2, DDT | TSHR 225/4885ATM 4170/4885MAPK1 2290/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.